Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics
The obesity epidemic is closely associated with the rising prevalence and severity of
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …
Alcohol-associated liver disease
B Mackowiak, Y Fu, L Maccioni… - The Journal of Clinical …, 2024 - Am Soc Clin Investig
Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …
and comprises a spectrum of several different disorders, including simple steatosis …
Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors
S Francque, G Szabo, MF Abdelmalek… - Nature reviews …, 2021 - nature.com
The increasing epidemic of obesity worldwide is linked to serious health effects, including
increased prevalence of type 2 diabetes mellitus, cardiovascular disease and nonalcoholic …
increased prevalence of type 2 diabetes mellitus, cardiovascular disease and nonalcoholic …
Immunological mechanisms and therapeutic targets of fatty liver diseases
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting
Alcohol-related liver disease (ALD), which includes a range of disorders of different severity
and is one of the most prevalent types of liver disease worldwide, has recently regained …
and is one of the most prevalent types of liver disease worldwide, has recently regained …
Inflammatory pathways in alcoholic steatohepatitis
Inflammatory processes are primary contributors to the development and progression of
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …
[HTML][HTML] Invited review liver fibrosis in NAFLD/NASH: From pathophysiology towards diagnostic and therapeutic strategies
Liver fibrosis, as an excess deposition of extracellular matrix (ECM) components, results
from chronic liver injury as well as persistent activation of inflammatory response and of …
from chronic liver injury as well as persistent activation of inflammatory response and of …
Hepatic stellate cell-immune interactions in NASH
JK Carter, SL Friedman - Frontiers in Endocrinology, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) is the dominant cause of liver disease worldwide.
Nonalcoholic steatohepatitis (NASH), a more aggressive presentation of NAFLD, is …
Nonalcoholic steatohepatitis (NASH), a more aggressive presentation of NAFLD, is …
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer
N Li, X Zhang, J Zhou, W Li, X Shu, Y Wu… - Advanced Drug Delivery …, 2022 - Elsevier
A growing body of multiscale biomechanical studies has been proposed to highlight the
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …
Tumor-associated neutrophils in hepatocellular carcinoma pathogenesis, prognosis, and therapy
Simple Summary Hepatocellular carcinoma is the most prevalent primary liver cancer,
accounting for> 80% of primary liver cancers worldwide. Inflammation has come to light as a …
accounting for> 80% of primary liver cancers worldwide. Inflammation has come to light as a …