[HTML][HTML] The association of systemic inflammatory biomarkers with non-alcoholic fatty liver disease: a large population-based cross-sectional study

W Sun, Y Fang, B Zhou, G Mao, J Cheng… - Preventive medicine …, 2024 - Elsevier
Purpose The aim of this study was to explore the relationship between non-alcoholic fatty
liver disease (NAFLD) and the two blood inflammatory markers including the systemic …

[HTML][HTML] Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis

AD Kim, SE Kim, A Leszczynska, B Kaufmann… - Scientific Reports, 2021 - nature.com
Inflammatory changes in the liver represent a key feature of non-alcoholic steatohepatitis
(NASH), the progressive form of non-alcoholic fatty liver disease (NAFLD). Innate immune …

The “Domino effect” in MASLD: The inflammatory cascade of steatohepatitis

K Mladenić, M Lenartić, S Marinović… - European Journal of …, 2024 - Wiley Online Library
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is an increasingly
common complication of obesity, affecting over a quarter of the global adult population. A …

[HTML][HTML] Obesity in acute alcoholic hepatitis increases morbidity and mortality

R Parker, SJ Kim, GY Im, J Nahas, B Dhesi, N Vergis… - …, 2019 - thelancet.com
Background Alcohol and obesity synergise to increase the risk of liver-related mortality. We
examined the influence of adiposity on clinical outcomes in alcoholic hepatitis (AH) and the …

When healing turns into killing–the pathophysiology of pancreatic and hepatic fibrosis

PE Ferdek, D Krzysztofik, KB Stopa… - The Journal of …, 2022 - Wiley Online Library
Disorders such as pancreatic or hepatic fibrosis are a cruel reminder that disruption of the
delicate physiological balance could result in severe pathological consequences. Fibrosis is …

Pericytes in the liver

E Kostallari, VH Shah - Pericyte Biology in Different Organs, 2019 - Springer
Liver pericytes, commonly named hepatic stellate cells (HSCs), reside in the space between
liver sinusoidal endothelial cells (LSECs) and hepatocytes. They display important roles in …

Mitochondrial dysfunction and mitochondrion-targeted therapeutics in liver diseases

L Xiang, Y Shao, Y Chen - Journal of Drug Targeting, 2021 - Taylor & Francis
The liver is a vital metabolic and detoxifying organ and suffers diverse endogenous or
exogenous damage. Hepatocyte mitochondria experience various structural and functional …

Evaluation of nonalcoholic fatty liver disease (NAFLD) in severe obesity using noninvasive tests and imaging techniques

W Theel, BM Boxma‐de Klerk… - Obesity …, 2022 - Wiley Online Library
The prevalence of nonalcoholic fatty liver disease (NAFLD) and the more severe and
inflammatory type, nonalcoholic steatohepatitis (NASH), is increasing rapidly. Especially in …

Phoenixin 14 inhibits high-fat diet-induced non-alcoholic fatty liver disease in experimental mice

F Yang, P Huang, L Shi, F Liu, A Tang… - Drug Design …, 2020 - Taylor & Francis
Introduction Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic
liver diseases. The development of NAFLD is closely associated with hepatic lipotoxicity …

Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis

A Torres-Hernandez, W Wang, Y Nikiforov, K Tejada… - Oncogene, 2019 - nature.com
Liver fibrosis and fibrosis-associated hepatocarcinogenesis are driven by chronic
inflammation and are leading causes of morbidity and death worldwide. SYK signaling …