Simple Summary In this review, we analyze the contribution of the most abundant immune
cell populations in hepatocellular carcinoma (HCC) progression and response to therapy …

Caloric overconsumption in vertebrates promotes adipose and liver fat accumulation while
perturbing the gut microbiome. This triad triggers pattern recognition receptor (PRR) …

Alcohol-associated liver disease (ALD) is a major contributor to liver-related mortality
globally. A growing body of evidence underscores the pivotal role of platelets throughout the …

Impaired self-renewal of Kupffer cells (KCs) leads to inflammation in metabolic dysfunction-
associated steatohepatitis (MASH). Here, we identify neutrophil cytosolic factor 1 (NCF1) as …

Objective Alcohol use in metabolic dysfunction-associated steatohepatitis (MASH) is
associated with an increased risk of fibrosis and liver-related death. Here, we aimed to …

The liver is a complicated heterogeneous organ composed of different cells. Parenchymal
cells called hepatocytes and various nonparenchymal cells, including immune cells and …

Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases. NAFLD
can further progress to irreversible liver failure such as non-alcoholic steatohepatitis (NASH) …

microRNA-21 (miRNA) is one of the most abundant miRNAs in chronic liver injuries
including alcoholic liver injury. Previous studies have demonstrated that miR-21 plays a role …

Neutrophils are the most abundant circulating granulocytes, linking innate and adaptive
immunity. Neutrophils can regulate inflammatory and immune responses through …

Objective: Paeonol is a natural phenolic component isolated from the root bark of peony with
multiple pharmacological activities. We investigated the anti-fibrotic effect and underlying …