Metabolic Dysfunction-Associated Steatotic Liver (MASL), previously named nonalcoholic
fatty liver (NAFL), is a multifactorial disease in which metabolic, genetic, and environmental …

Alcohol-associated hepatitis (AH) is an acute-on-chronic liver injury that occurs in patients
with chronic alcohol-associated liver disease (ALD). Patients with severe AH have high short …

Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by a rapid
deterioration of previously well-compensated chronic liver diseases. One of the main …

肝纤维化是慢性肝脏损伤的共同结果, 可进展为肝硬化甚至是肝癌, 目前尚无有效逆转肝纤维化
的手段. 在窦周隙中被激活的肝星状细胞转变为肌成纤维细胞并分泌胶原, 是肝纤维化进程中的 …

Chemokines play a critical role in cell migration and activation through binding to G-protein
coupled cell-surface receptors with seven transmembrane domains. Chemokines are …

Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a societal
burden due to the lack of effective treatment and incomplete pathophysiology …

Defining the immune physiology of culture-adapted mesenchymal stromal cells (MSCs)
derived from distinct tissue compartments informs their potential utility as pharmaceuticals …

Background: HIV and HCV coinfection leads to accelerated liver fibrosis, in which microbial
translocation and systemic inflammation might play important roles. Objective: This study …

In the last decades, the use of nanocarriers for immunotherapeutic purposes has gained a
lot of attention, especially in the field of tumor therapy. However, most types of nanocarriers …

Although methionine sulfoxide reductase (Msr) is known to modulate the activity of multiple
functional proteins, the roles of Msr in pancreatic stellate cell physiology have not been …