[HTML][HTML] Insights on the use of α-lipoic acid for therapeutic purposes
α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants,
animals, and humans. It has various properties, among them great antioxidant potential and …
animals, and humans. It has various properties, among them great antioxidant potential and …
Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain
M Sisignano, R Baron, K Scholich… - Nature Reviews …, 2014 - nature.com
Chemotherapy-induced peripheral neuropathic pain (CIPNP)—a severe adverse effect
observed in up to 80% of patients during treatment with antineoplastic drugs—limits the …
observed in up to 80% of patients during treatment with antineoplastic drugs—limits the …
Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications
N Apostolova, VM Victor - Antioxidants & redox signaling, 2015 - liebertpub.com
Mitochondrial function and specifically its implication in cellular redox/oxidative balance is
fundamental in controlling the life and death of cells, and has been implicated in a wide …
fundamental in controlling the life and death of cells, and has been implicated in a wide …
Therapeutic applications of PARP inhibitors: anticancer therapy and beyond
The aim of this article is to describe the current and potential clinical translation of
pharmacological inhibitors of poly (ADP-ribose) polymerase (PARP) for the therapy of …
pharmacological inhibitors of poly (ADP-ribose) polymerase (PARP) for the therapy of …
[HTML][HTML] Functional metagenomic profiling of intestinal microbiome in extreme ageing
Age-related alterations in human gut microbiota composition have been thoroughly
described, but a detailed functional description of the intestinal bacterial coding capacity is …
described, but a detailed functional description of the intestinal bacterial coding capacity is …
[HTML][HTML] Mitochondrial dysfunction and chronic disease: treatment with natural supplements
GL Nicolson - Integrative Medicine: A Clinician's Journal, 2014 - ncbi.nlm.nih.gov
Loss of function in mitochondria, the key organelle responsible for cellular energy
production, can result in the excess fatigue and other symptoms that are common complaints …
production, can result in the excess fatigue and other symptoms that are common complaints …
[HTML][HTML] Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed
MF Wipperman, DW Fitzgerald, MAJ Juste, Y Taur… - Scientific reports, 2017 - nature.com
Mycobacterium tuberculosis, the cause of Tuberculosis (TB), infects one third of the world's
population and causes substantial mortality worldwide. In its shortest format, treatment of TB …
population and causes substantial mortality worldwide. In its shortest format, treatment of TB …
New insights into antioxidant strategies against paraquat toxicity
T Blanco-Ayala, AC Andérica-Romero… - Free radical …, 2014 - Taylor & Francis
Abstract Paraquat (PQ, 1, 1'-dimethyl-4-4'-bipyridinium dichloride) is a highly toxic
quaternary ammonium herbicide widely used in agriculture, it exerts its toxic effects mainly …
quaternary ammonium herbicide widely used in agriculture, it exerts its toxic effects mainly …
Dihydrolipoic acid–gold nanoclusters regulate microglial polarization and have the potential to alter neurogenesis
Microglia-mediated neuroinflammation is one of the most significant features in a variety of
central nervous system (CNS) disorders such as traumatic brain injury, stroke, and many …
central nervous system (CNS) disorders such as traumatic brain injury, stroke, and many …
Medicinal plants used for treatment of diabetes by the Marakh sect of the Garo tribe living in Mymensingh district, Bangladesh
M Rahmatullah, NK Azam, Z Khatun, S Seraj… - African Journal of …, 2012 - ajol.info
Diabetes mellitus is an endocrinological disorder arising from insulin deficiency or due to
ineffectiveness of the insulin produced by the body. This results in high blood glucose and …
ineffectiveness of the insulin produced by the body. This results in high blood glucose and …