Sleep plays an essential role in all studied animals with a nervous system. However, sleep
deprivation leads to various pathological changes and neurobehavioral problems …

We have previously shown that selective inhibition of histone deacetylase 3 (HDAC3)
decreases infarct volume and improves long-term functional outcomes after stroke. In this …

Stroke is a group of diseases resulting from cerebral vascular rupture or obstruction and
subsequent brain blood circulation disorder, leading to rapid neurological deficits. Ischemic …

Metabolic microenvironment dysfunction remains hallmarks of acute ischemic stroke (AIS)
throughout the ischemia, reperfusion, and recovery stages. Existing therapeutic strategies …

Alzheimer's disease (AD) is a chronic multifactorial and complex neuro-degenerative
disorder characterized by memory impairment and the loss of cognitive ability, which is a …

Stroke is the third leading cause of death and long-term disability in the world. Considered
largely a disease of aging, its global economic and healthcare burden is expected to rise as …

More and more evidence shows that the pathological mechanism of vascular dementia (VD)
is closely related to oxidative stress injury, cell apoptosis, autophagy, inflammatory …

As a leading cause of mortality and morbidity, stroke constitutes a significant global health
burden. Ischemic stroke accounts for 80% of cases and occurs due to an arterial thrombus …

Autophagy is a self-defense and self-degrading intracellular system involved in the recycling
and elimination of the payload of cytoplasmic redundant components, aggregated or …

Harmonic mechanisms orchestrate neurogenesis in the healthy brain within specific
neurogenic niches, which generate neurons from neural stem cells as a homeostatic …