Stroke is a main cause of disability and death among adults in China, and acute ischemic
stroke accounts for 80% of cases. The key to ischemic stroke treatment is to recanalize the …

Ischaemic stroke causes neuron loss and long-term functional deficits. Unfortunately,
effective approaches to preserving neurons and promoting functional recovery remain …

Stroke is an acute cerebrovascular disease resulting from either obstruction or rupture of a
blood vessel in the brain. Oxidative stress (OS), referred to a status where cellular oxidative …

Neurological disorders are diverse, have complex causes, and often result in disability; yet,
effective treatments remain scarce. The resveratrol derivative pterostilbene possesses …

A major hallmark of neuroinflammation is the activation of microglia and astrocytes with the
induction of inflammatory mediators such as IL‐1β, TNF‐α, iNOS, and IL‐6 …

Stroke is one of the main causes of death in the US and post-stroke treatment options
remain limited. Ischemic stroke is caused by a blood clot that compromises blood supply to …

Neurodegeneration of the brain after ischemia is a major cause of severe, long-term
disability, dementia, and mortality, which is a global problem. These phenomena are …

The endothelial dysfunction, associated with inflammation and vascular permeability,
remains the key event in the pathogenesis of cerebral ischemic stroke. Angiogenesis is …

As the first peripheral immune cells to enter the brain after ischemic stroke, neutrophils are
important participants in stroke-related neuroinflammation. Neutrophils are quickly mobilized …

Astrocytes are the most abundant glial cells in the central nervous system. These cells are
an important hub for intercellular communication. They participate in various …