Nifedipine 1 is an antagonist of calcium influx through the slow channel of the cell
membrane and has been shown to be an effective and relatively well-tolerated treatment for …

The calcium antagonists diltiazem, nifedipine and verapamil are widely used in the
treatment of coronary heart disease, arterial hypertension, certain supraventricular …

Numerous pharmacological agents have been shown to produce clinically significant
pharmacokinetic interactions with digoxin. Drugs which reduce digoxin absorption include …

Although digpxin is often the first choice for control of ventricular response in chronic atrial
fibrillation, it fails to slow exercise rates. Diltiazem, a calcium channel antagonist that slows …

A multiple‐dose, open‐label, two‐period, crossover randomized study was conducted in 12
healthy male volunteers to investigate the effect of multiple‐dose telmisartan on the steady …

Nimodipine is indicated for a variety of conditions in elderly patients. Elderly patients often
have multiple morbidity and receive treatment with a variety of drugs. Therefore, it is …

LLOYD H. SMITH, JR, MD:* It is routine to ask each chief medical resident at Moffitt Hospital
to present a medical staffconference near the completion ofhis or her tour ofduty in that …

The pharmacokinetic and pharmacodynamic interactions between digoxin and propafenone
were investigated in 10 hospitalized patients with heart disease and cardiac arrhythmias …

Synopsis Diltiazem is a benzothiazepine derivative calcium antagonist available in several
formulations, some of which enable once daily administration. The drug as monotherapy has …

Since calcium channel antagonists are a diverse class of drugs frequently administered in
combination with other agents, the potential for clinically significant pharmacokinetic drug …