The synovium is the major target tissue of inflammatory arthritides such as rheumatoid
arthritis. The study of synovial tissue has advanced considerably throughout the past few …

Blood platelets have long been recognised to bring about primary haemostasis with
deficiencies in platelet production and function manifesting in bleeding while upregulated …

Post-traumatic arthritis (PTA) develops after an acute direct trauma to the joints. PTA causes
about 12% of all osteoarthritis cases, and a history of physical trauma may also be found in …

Joint trauma can lead to a spectrum of acute lesions, including osteochondral fractures,
ligament or meniscus tears and damage to the articular cartilage. This is often associated …

The synovial joint contains synovial fluid (SF) within a cavity bounded by articular cartilage
and synovium. SF is a viscous fluid that has lubrication, metabolic, and regulatory functions …

Rheumatoid arthritis (RA) is considered to be an inflammatory disorder whereas OA is not
an overtly inflammatory disorder as RA but certain inflammatory cytokines and periodic …

Synovial immunopathology in rheumatoid arthritis is complex involving both resident and
infiltrating cells. The synovial tissue undergoes significant neovascularization, facilitating an …

Cartilage destruction in osteoarthritis (OA) is thought to be mediated by two main enzyme
families; the matrix metalloproteinases (MMPs) are responsible for cartilage collagen …

While research in osteoarthritis has focused on the events that lead to the destruction of
articular cartilage, recent evidence suggests that two other components of the joints—bone …

Tissue‐reactive graft copolymers were designed to protect the cartilage against enzymatic
degradation and restore its lubrication properties during the early stages of osteoarthritis …