[HTML][HTML] Identification of prognostic immune-related genes in the tumor microenvironment of endometrial cancer

P Chen, Y Yang, Y Zhang, S Jiang, X Li… - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Endometrial cancer (EC) is one of the most common gynecologic malignancies. To identify
potential prognostic biomarkers for EC, we analyzed the relationship between the EC tumor …

[HTML][HTML] Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma

Y Qin, X Zheng, W Gao, B Wang, Y Wu - Molecular Therapy-Oncolytics, 2021 - cell.com
Head and neck squamous cell carcinomas (HNSCCs) are a type of common malignant
tumor, mainly manifesting as oropharyngeal, oral cavity, laryngopharyngeal …

[HTML][HTML] A subtype of cancer-associated fibroblasts with lower expression of alpha-smooth muscle actin suppresses stemness through BMP4 in oral carcinoma

AK Patel, K Vipparthi, V Thatikonda, I Arun… - Oncogenesis, 2018 - nature.com
Cancer-associated fibroblasts (CAFs) demonstrate the characteristics of myofibroblast
differentiation by often expressing the ultrastructure of alpha-smooth muscle actin (αSMA) …

Ionizing radiation sensitizes tumors to PD-L1 immune checkpoint blockade in orthotopic murine head and neck squamous cell carcinoma

A Oweida, S Lennon, D Calame, S Korpela… - …, 2017 - Taylor & Francis
Immunotherapy clinical trials targeting the programmed-death ligand axis (PD-1/PD-L1)
show that most head and neck squamous cell carcinoma (HNSCC) patients are resistant to …

[HTML][HTML] The role of T-cells in head and neck squamous cell carcinoma: from immunity to immunotherapy

MPS Damasio, CS Nascimento, LM Andrade… - Frontiers in …, 2022 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) encompass a group of complex entities
of tumours affecting the aerodigestive upper tract. The main risk factors are strongly related …

[HTML][HTML] Clinical relevance of the tumor microenvironment and immune escape of oral squamous cell carcinoma

AW Eckert, C Wickenhauser, PC Salins… - Journal of translational …, 2016 - Springer
Background Changes in the tumor microenvironment and immune surveillance represent
crucial hallmarks of various kinds of cancer, including oral squamous cell carcinoma …

[HTML][HTML] Precision medicine approaches to overcome resistance to therapy in head and neck cancers

S Ortiz-Cuaran, J Bouaoud, A Karabajakian… - Frontiers in …, 2021 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is the sixth most incident cancer
worldwide. More than half of HNSCC patients experience locoregional or distant relapse to …

[HTML][HTML] Single-cell profiling reveals heterogeneity of primary and lymph node metastatic tumors and immune cell populations and discovers important prognostic …

Z Wang, H Zhang, Y Zhai, F Li, X Shi… - Frontiers in …, 2022 - frontiersin.org
Although substantial progress has been made in biological research and clinical treatment
in recent years, the clinical prognosis of oral squamous cell carcinoma (OSCC) is still not …

[HTML][HTML] Transforming growth factor‑β signaling in head and neck squamous cell carcinoma: Insights into cellular responses

X Pang, YL Tang, XH Liang - Oncology letters, 2018 - spandidos-publications.com
Head and neck squamous cell carcinoma (HNSCC) arises in the oral cavity, salivary glands,
larynx, pharynx, nasal cavity and paranasal sinuses, and is characterized by high morbidity …

[HTML][HTML] Tumor microenvironment and immunotherapy response in head and neck cancer

P Economopoulou, I Kotsantis, A Psyrri - Cancers, 2020 - mdpi.com
Simple Summary Immunotherapy has revolutionized cancer treatment and has been
integrated in the treatment algorithm of metastatic head and neck cancer. Despite robust …