Making a good egg: human oocyte health, aging, and in vitro development

EE Telfer, J Grosbois, YL Odey… - Physiological …, 2023 - journals.physiology.org
Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

[HTML][HTML] Signaling mechanisms and their regulation during in vivo or in vitro maturation of mammalian oocytes

P Strączyńska, K Papis, E Morawiec… - Reproductive Biology …, 2022 - Springer
In vitro fertilization (IVF) is currently one of the most effective methods of infertility treatment.
An alternative to commonly used ovarian hyperstimulation can become extracorporeal …

Novel signaling mechanisms in the ovary during oocyte maturation and ovulation

M Conti, M Hsieh, AM Zamah, JS Oh - Molecular and cellular …, 2012 - Elsevier
During the peri-ovulatory period, the gonadotropin LH triggers major changes in both the
somatic and germ cell compartments of the ovarian follicle. The oocyte completes the …

[HTML][HTML] Oocyte maturation and quality: role of cyclic nucleotides

RB Gilchrist, AM Luciano, D Richani, HT Zeng… - …, 2016 - rep.bioscientifica.com
The developing fetus requires substantial amounts of fatty acids to support rapid cellular
growth and activity. Although the fatty acid composition delivered to the fetus is largely …

Minireview: functions of the cumulus oophorus during oocyte maturation, ovulation, and fertilization.

S Tanghe, A Soom, H Nauwynck, M Coryn, A Kruif - 2002 - cabidigitallibrary.org
The function that cumulus cells play during oocyte maturation ie, in keeping the oocyte
under arrest, in participating in the induction of meiotic resumption and in supporting …

The human oocyte and cumulus cells relationship: new insights from the cumulus cell transcriptome

Z Huang, D Wells - Molecular human reproduction, 2010 - academic.oup.com
It is widely recognized that bi-directional communication exists between the human oocyte
and cumulus cells (CCs) which is essential for the production of competent oocytes. CCs …

Biological role of connexin intercellular channels and hemichannels

R Kar, N Batra, MA Riquelme, JX Jiang - Archives of biochemistry and …, 2012 - Elsevier
Gap junctions (GJ) and hemichannels (HC) formed from the protein subunits called
connexins are transmembrane conduits for the exchange of small molecules and ions …

Recent insights into oocyte–follicle cell interactions provide opportunities for the development of new approaches to in vitro maturation

RB Gilchrist - Reproduction, Fertility and Development, 2010 - CSIRO Publishing
The last 5–10 years of research in ovarian and oocyte biology has delivered some major
new advances in knowledge of the molecular and cellular processes regulating oocyte …

Role of cyclic nucleotide signaling in oocyte maturation

M Conti, CB Andersen, F Richard, C Mehats… - Molecular and cellular …, 2002 - Elsevier
The development of the ovarian follicle, oocyte maturation, and ovulation require a complex
set of endocrine, paracrine, and autocrine inputs that are translated into the regulation of …

[PDF][PDF] Impact of linoleic acid on bovine oocyte maturation and embryo development

WF Marei, DC Wathes, AA Fouladi-Nashta - Reproduction, 2010 - academia.edu
Abstract Linoleic acid (LA; 18: 2 n-6) is the most abundant fatty acid in bovine follicular fluid,
and it was previously reported that LA concentration significantly decreases when follicle …