The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

Antimicrobial resistance (AMR) and the associated morbidity and mortality due to bacterial
pathogens have been increasing globally to alarming levels. The World Health Organization …

Background Gonorrhoea is a major global public health problem that is exacerbated by drug
resistance. Effective vaccine development has been unsuccessful, but surveillance data …

La introducción de los antibióticos en la práctica clínica supuso una de las intervenciones
más importantes para el control de las enfermedades infecciosas. Los antibióticos han …

Background Neisseria gonorrhoeae is acquiring increasing resistance to available oral
antibiotics, and current screening and treatment approaches have not decreased gonorrhea …

Gonorrhea, an obligate human infection, is on the rise worldwide and gonococcal strains
resistant to many antibiotics are emerging. Appropriate antimicrobial treatment and …

An estimated 499 million curable sexually transmitted infections (STIs; gonorrhea,
chlamydia, syphilis, and trichomoniasis) occurred globally in 2008. In addition, well over 500 …

Etiology, transmission and protection: Neisseria gonorrhoeae (the gonococcus) is the
etiological agent for the strictly human sexually transmitted disease gonorrhea. Infections …

Neisseria gonorrhoeae infection (gonorrhoea) is a global public health challenge, causing
substantial sexual and reproductive health consequences, such as infertility, pregnancy …

Female mice were immunized intravaginally with gonococcal outer membrane vesicles
(OMVs) plus microencapsulated interleukin-12 (IL-12), and challenged using an established …