Host response mechanisms in periodontal diseases

N Silva, L Abusleme, D Bravo, N Dutzan… - Journal of Applied Oral …, 2015 - SciELO Brasil
Periodontal diseases usually refer to common inflammatory disorders known as gingivitis
and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm …

The role of neutrophils in inflammation resolution

HR Jones, CT Robb, M Perretti, AG Rossi - Seminars in immunology, 2016 - Elsevier
The fundamental role played by neutrophils for an efficient, acute inflammatory response
has long been appreciated, with the underlying molecular and cellular mechanisms largely …

Oral dysbiosis and autoimmunity: from local periodontal responses to an imbalanced systemic immunity. A review

LJ Suárez, H Garzón, S Arboleda… - Frontiers in …, 2020 - frontiersin.org
The current paradigm of onset and progression of periodontitis includes oral dysbiosis
directed by inflammophilic bacteria, leading to altered resolution of inflammation and lack of …

Oral biofilms from symbiotic to pathogenic interactions and associated disease–connection of periodontitis and rheumatic arthritis by peptidylarginine deiminase

K Kriebel, C Hieke, B Müller-Hilke, M Nakata… - Frontiers in …, 2018 - frontiersin.org
A wide range of bacterial species are harbored in the oral cavity, with the resulting complex
network of interactions between the microbiome and host contributing to physiological as …

Mechanisms involved in the association between peridontal diseases and cardiovascular disease

R Teles, CY Wang - Oral diseases, 2011 - Wiley Online Library
Oral Diseases (2011) 17, 450–461 It is now well accepted that besides the cholesterol
associated mechanisms of atherogenesis, inflammation plays a crucial role in all stages of …

Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of primary epithelial cells infected with the periodontal pathogen Porphyromonas …

O Yilmaz, T Jungas, P Verbeke… - Infection and immunity, 2004 - Am Soc Microbiol
Porphyromonas gingivalis, an important periodontal pathogen, infects primary gingival
epithelial cells (GECs). Despite the large number of bacteria that replicate inside the GECs …

Hyperactivity and reactivity of peripheral blood neutrophils in chronic periodontitis

JB Matthews, HJ Wright, A Roberts… - Clinical & …, 2007 - academic.oup.com
Some evidence exists that peripheral neutrophils from patients with chronic periodontitis
generate higher levels of reactive oxygen species (ROS) after Fcγ-receptor stimulation than …

[PDF][PDF] Host-derived diagnostic markers for periodontitis: do they exist in gingival crevice fluid?

BG Loos, S Tjoa - Periodontology 2000, 2005 - academia.edu
In all fields of medicine, investigators are searching for useful biological diagnostic markers.
An ideal diagnostic marker should indicate the presence of a disease process before …

Manipulation of Neutrophils by Porphyromonas gingivalis in the Development of Periodontitis

M Sochalska, J Potempa - Frontiers in cellular and infection …, 2017 - frontiersin.org
The pathogenesis of the chronic periodontal disease is associated with a skewed host
inflammatory response to periodontal pathogens, such as Porphyromonas gingivalis, that …

Effects of periodontal therapy on GCF cytokines in generalized aggressive periodontitis subjects

AP de Lima Oliveira, M de Faveri… - Journal of clinical …, 2012 - Wiley Online Library
Aim To examine changes in levels of gingival crevicular fluid (GCF) cytokines, after
periodontal therapy of generalized aggressive periodontitis (GAgP). Materials and Methods …