Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

[HTML][HTML] Vulvovaginal candidiasis: a current understanding and burning questions

HME Willems, SS Ahmed, J Liu, Z Xu, BM Peters - Journal of Fungi, 2020 - mdpi.com
Candida albicans, along with other closely related Candida species, are the primary
causative agents of vulvovaginal candidiasis (VVC)—a multifactorial infectious disease of …

Fungal dysbiosis: immunity and interactions at mucosal barriers

ID Iliev, I Leonardi - Nature Reviews Immunology, 2017 - nature.com
Fungi and mammals share a co-evolutionary history and are involved in a complex web of
interactions. Studies focused on commensal bacteria suggest that pathological changes in …

[HTML][HTML] Recurrent vulvovaginal candidiasis: an immunological perspective

D Rosati, M Bruno, M Jaeger, J Ten Oever, MG Netea - Microorganisms, 2020 - mdpi.com
Vulvovaginal candidiasis (VVC) is a widespread vaginal infection primarily caused by
Candida albicans. VVC affects up to 75% of women of childbearing age once in their life …

Effects of intestinal fungi and viruses on immune responses and inflammatory bowel diseases

ID Iliev, K Cadwell - Gastroenterology, 2021 - Elsevier
The intestinal microbiota comprises diverse fungal and viral components, in addition to
bacteria. These microbes interact with the immune system and affect human physiology …

[HTML][HTML] IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

RG Iannitti, V Napolioni, V Oikonomou… - Nature …, 2016 - nature.com
Dysregulated inflammasome activation contributes to respiratory infections and pathologic
airway inflammation. Through basic and translational approaches involving murine models …

Roles of the gut virome and mycobiome in faecal microbiota transplantation

S Lam, X Bai, AN Shkoporov, H Park, X Wu… - The Lancet …, 2022 - thelancet.com
Faecal microbiota transplantation (FMT) is an innovative approach to treat diseases that are
associated with gut dysbiosis, by transferring a healthy stool microbiota to a recipient with …

Candidalysin drives epithelial signaling, neutrophil recruitment, and immunopathology at the vaginal mucosa

JP Richardson, HME Willems, DL Moyes… - Infection and …, 2018 - Am Soc Microbiol
Unlike other forms of candidiasis, vulvovaginal candidiasis, caused primarily by the fungal
pathogen Candida albicans, is a disease of immunocompetent and otherwise healthy …

Mitochondrial dysfunction in atherosclerosis

W Peng, G Cai, Y Xia, J Chen, P Wu, Z Wang… - DNA and cell …, 2019 - liebertpub.com
Mitochondria are highly dynamic organelles beyond powerhouses of a cell. These
components also play important roles in cell homeostasis by regulating cell function and …