Bacteria have to cope with oxidative stress caused by distinct Reactive Oxygen Species
(ROS), derived not only from normal aerobic metabolism but also from oxidants present in …

Small regulatory RNA (sRNAs) are key mediators of posttranscriptional gene control in
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …

Metal ions are essential for many reactions, but excess metals can be toxic. In bacteria,
metal limitation activates pathways that are involved in the import and mobilization of metals …

Efforts to construct synthetic networks in living cells have been hindered by the limited
number of regulatory components that provide wide dynamic range and low crosstalk. Here …

The excessive consumption of fossil fuels causes massive emission of CO2, leading to
climate deterioration and environmental pollution. The development of substitutes and …

Oxic environments are hazardous. Molecular oxygen adventitiously abstracts electrons from
many redox enzymes, continuously forming intracellular superoxide and hydrogen peroxide …

The overall composition of the mammalian intestinal microbiota varies between individuals:
within each individual there are differences along the length of the intestinal tract related to …

Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

Staphylococcus aureus is an eminent human pathogen that can colonize the human host
and cause severe life-threatening illnesses. This bacterium can reside in and infect a wide …

The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …