Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the American Thyroid Association's …

Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of
the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is …

Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

The NCCN Guidelines for Thyroid Carcinoma provide recommendations for the
management of different types of thyroid carcinoma, including papillary, follicular, Hürthle …

Background: Mutations of v-raf murine sarcoma viral oncogene homolog B (BRAF) are
commonly identified in papillary and anaplastic thyroid carcinoma and are associated with …

Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid cancer. It shows a
wide spectrum of morphological presentations and the diagnosis could be challenging due …

Background: Some patients with metastatic differentiated thyroid cancer (DTC) lack iodine
avidity and are therefore unsuitable for radioactive iodine (RAI) therapy. Limited experience …

Introduction The use of molecular markers, especially BRAF and TERT promoter mutations,
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …

Context Little is known about the frequency of key mutations in thyroid cancer metastases
and its relationship with the primary tumor genotype. Objectives To evaluate the frequency of …

Objective Transcriptional activating mutations in the promoter of the telomerase reverse
transcriptase (TERT) gene were reported at high frequency in aggressive poorly …