Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Strategic Design of Luminescent Rhenium (I), Ruthenium (II), and Iridium (III) Complexes as Activity‐Based Probes for Bioimaging and Biosensing

LCC Lee, KKW Lo - Chemistry–An Asian Journal, 2022 - Wiley Online Library
The rapid development of responsive fluorescent probes has advanced optical imaging for
biological research and biomedical applications. Among different sensing strategies, activity …

Engineered bacteria labeled with iridium (III) photosensitizers for enhanced photodynamic immunotherapy of solid tumors

W Lin, Y Liu, J Wang, Z Zhao, K Lu, H Meng… - Angewandte …, 2023 - Wiley Online Library
Despite metal‐based photosensitizers showing great potential in photodynamic therapy for
tumor treatment, the application of the photosensitizers is intrinsically limited by their poor …

Reduction of Platinum (IV) Prodrug Hemoglobin Nanoparticles with Deeply Penetrating Ultrasound Radiation for Tumor‐Targeted Therapeutically Enhanced …

G Liang, T Sadhukhan, S Banerjee… - Angewandte Chemie …, 2023 - Wiley Online Library
The development of PtIV prodrugs that are reduced into the therapeutically active PtII
species within the tumor microenvironment has received much research interest. In order to …

Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium (III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and …

J Kasparkova, A Hernández-García… - Journal of Medicinal …, 2023 - ACS Publications
A second-generation series of biscyclometalated 2-(5-aryl-thienyl)-benzimidazole and-
benzothiazole Ir (III) dppz complexes [Ir (C^ N) 2 (dppz)]+, Ir1–Ir4, were rationally designed …

Design of near-infrared-triggered metallo-photosensitizers via a self-assembly-induced vibronic decoupling strategy

J Zhao, Y Gao, R Huang, C Chi, Y Sun… - Journal of the …, 2023 - ACS Publications
Development of highly efficient near-infrared (NIR)-excited photosensitizers is hampered by
the fast nonradiative vibrational relaxation process regulated by the energy gap law. Here …

Isomer engineering of lepidine-based iridophosphors for far-red hypoxia imaging and photodynamic therapy

P Tao, Z Lv, XK Zheng, H Jiang, S Liu, H Wang… - Inorganic …, 2022 - ACS Publications
The development of highly efficient cyclometalated phosphorescent iridium (III) complexes is
greatly promoted by their rational molecular design. Manipulating the excited states of …

Bioorthogonally Assisted Phototherapy: Recent Advances and Prospects

E Kozma, M Bojtár, P Kele - Angewandte Chemie International …, 2023 - Wiley Online Library
Photoresponsive materials offer excellent spatiotemporal control over biological processes
and the emerging phototherapeutic methods are expected to have significant effects on …

Novel Re(I) Complexes as Potential Selective Theranostic Agents in Cancer Cells and In Vivo in Caenorhabditis elegans Tumoral Strains

A Marco, P Ashoo, S Hernández-García… - Journal of Medicinal …, 2024 - ACS Publications
A series of rhenium (I) complexes of the type fac-[Re (CO) 3 (N^ N) L] 0/+, Re1–Re9, was
synthesized, where N^ N= benzimidazole-derived bidentate ligand with an ester …

Bithiophene‐Functionalized Infrared Two‐Photon Absorption Metal Complexes as Single‐Molecule Platforms for Synergistic Photodynamic, Photothermal, and …

XL Li, MF Wang, LZ Zeng, GK Li… - Angewandte Chemie …, 2024 - Wiley Online Library
A planar conjugated ligand functionalized with bithiophene and its Ru (II), Os (II), and Ir (III)
complexes have been constructed as single‐molecule platform for synergistic …