One Health Approaches to Trace Mycobacterium leprae's Zoonotic Potential Through Time

C Urban, AA Blom, S Pfrengle… - Frontiers in …, 2021 - frontiersin.org
Hansen's disease (leprosy), mainly caused by infection with Mycobacterium leprae, has
accompanied humanity for thousands of years. Although currently rare in Europe, there are …

Field-friendly anti-PGL-I serosurvey in children to monitor Mycobacterium leprae transmission in Bihar, India

L Pierneef, P Malaviya, A van Hooij, S Sundar… - Frontiers in …, 2023 - frontiersin.org
Background It has been amply described that levels of IgM antibodies against
Mycobacterium leprae (M. leprae) phenolic glycolipid I (PGL-I) correlate strongly with the …

Multiplex PCR-based RFLP assay for early identification of prevalent Mycobacterium leprae genotypes

P Dwivedi, M Sharma, P Singh - Diagnostic Microbiology and Infectious …, 2023 - Elsevier
Mycobacterium leprae is classified into four SNP genotypes and 16 subtypes (from 1A to 4P)
that exhibit phylogeographical association reported from around the world. Among them …

[HTML][HTML] Infection with Mycobacterium lepromatosis

DM Scollard - The American Journal of Tropical Medicine and …, 2016 - ncbi.nlm.nih.gov
Microbiologically speaking, the ancient scourge of leprosy has a new face. Considered a
curse for millennia, the causative agent, Mycobacterium leprae, was first described by …

Transmission of drug-resistant leprosy in Guinea-Conakry detected using molecular epidemiological approaches

C Avanzi, P Busso, A Benjak, C Loiseau… - Clinical Infectious …, 2016 - academic.oup.com
Molecular drug susceptibility testing was performed on skin biopsies from 24 leprosy
patients from Guinea-Conakry for the first time. We identified primary drug resistance in 4 …

[HTML][HTML] Pathogenesis, clinical considerations, and treatments: A narrative review on leprosy

PH Le, S Philippeaux, T Mccollins, C Besong, A Kellar… - Cureus, 2023 - ncbi.nlm.nih.gov
Hansen disease, known as Leprosy, is an infectious disease caused by Mycobacterium
leprae. The disease was once thought to be highly contiguous, and patients with leprosy …

[HTML][HTML] Mycobacterium leprae infection in a wild nine-banded armadillo, Nuevo León, Mexico

L Vera-Cabrera, CJ Ramos-Cavazos… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
Nine-banded armadillos (Dasypus novemcinctus) are naturally infected with Mycobacterium
leprae and are implicated in the zoonotic transmission of leprosy in the United States. In …

Simultaneous determination of Mycobacterium leprae drug resistance and single-nucleotide polymorphism genotype by use of nested multiplex PCR with amplicon …

Y Iwao, S Mori, M Ato, N Nakata - Journal of Clinical Microbiology, 2021 - Am Soc Microbiol
Mycobacterium leprae is the predominant cause of leprosy worldwide, and its genotypes
can be classified into four single-nucleotide polymorphism (SNP) types and 16 subtypes …

Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae

MLBM Arraes, MV Holanda, LNGC Lima… - Memorias do Instituto …, 2017 - SciELO Brasil
BACKGROUND The detection of live Mycobacterium leprae in soil and animals other than
humans suggests that the environment plays a role in the transmission of leprosy …

One Health and Hansen's disease in Brazil

P Deps, PS Rosa - PLoS Neglected Tropical Diseases, 2021 - journals.plos.org
The concept of One Health originated with the German pathologist Rudolf Virchow in the late
19th century but has become a global movement only in the past 2 decades [1]. One Health …