Current and promising applications of Hf (IV)-based MOFs in clinical cancer therapy

X Chen, M Li, M Lin, C Lu, A Kumar, Y Pan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancer is one of the greatest challenges in medical science today as it poses a serious
threat to human life. In view of this myriad of therapeutic strategies are being developed for …

Progress, challenges, and future of nanomedicine

C Zhang, L Yan, X Wang, S Zhu, C Chen, Z Gu, Y Zhao - Nano Today, 2020 - Elsevier
Nanotherapeutics exhibit unique advantages in clinical outcomes compared with
conventional small molecular drugs. The past three decades have seen intensive research …

NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma …

S Bonvalot, PL Rutkowski, J Thariat, S Carrère… - The Lancet …, 2019 - thelancet.com
Background Pathological complete response to preoperative treatment in adults with soft-
tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2 …

Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

Z Huang, Y Wang, D Yao, J Wu, Y Hu, A Yuan - Nature communications, 2021 - nature.com
Radiation therapy can potentially induce immunogenic cell death, thereby priming anti-
tumor adaptive immune responses. However, radiation-induced systemic immune …

Cancer nanomedicine: progress, challenges and opportunities

J Shi, PW Kantoff, R Wooster, OC Farokhzad - Nature reviews cancer, 2017 - nature.com
The intrinsic limits of conventional cancer therapies prompted the development and
application of various nanotechnologies for more effective and safer cancer treatment …

Inorganic nanoparticles in clinical trials and translations

H Huang, W Feng, Y Chen, J Shi - Nano Today, 2020 - Elsevier
The development and application of nanotechnology-related knowledge and tools in
modern medicine has been showing great potentials in elevating human's living standards …

Emerging nanotechnology and advanced materials for cancer radiation therapy

G Song, L Cheng, Y Chao, K Yang, Z Liu - Advanced materials, 2017 - Wiley Online Library
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

Nanoparticles in the clinic

AC Anselmo, S Mitragotri - Bioengineering & translational …, 2016 - Wiley Online Library
Nanoparticle/microparticle‐based drug delivery systems for systemic (ie, intravenous)
applications have significant advantages over their nonformulated and free drug …

Recent progress and trends in X-ray-induced photodynamic therapy with low radiation doses

L He, X Yu, W Li - ACS nano, 2022 - ACS Publications
The prominence of photodynamic therapy (PDT) in treating superficial skin cancer inspires
innovative solutions for its congenitally deficient shadow penetration of the visible-light …

Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications

A Wicki, D Witzigmann, V Balasubramanian… - Journal of controlled …, 2015 - Elsevier
Cancer is a leading cause of death worldwide. Currently available therapies are inadequate
and spur demand for improved technologies. Rapid growth in nanotechnology towards the …