The global prevalence of metabolic diseases such as type 2 diabetes mellitus,
steatohepatitis, myocardial infarction, and stroke has increased dramatically over the past …

Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …

The impact of sugar consumption on health continues to be a controversial topic. The
objective of this review is to discuss the evidence and lack of evidence that allows the …

Ceramides are products of metabolism that accumulate in individuals with obesity or
dyslipidaemia and alter cellular processes in response to fuel surplus. Their actions, when …

Muscle's structural composition is an important factor underlying muscle strength and
physical function in older adults. There is an increasing amount of research to support the …

Obesity represents a major risk factor for a plethora of severe diseases, including diabetes,
cardiovascular disease, non-alcoholic fatty liver disease, and cancer. It is often …

Diabetes mellitus is a serious disease affecting about 5% of people worldwide. Diabetes is
characterized by hyperglycemia and impairment in insulin secretion and/or action …

A growing body of evidence is pointing out the pathophysiological role of fat accumulation in
different organs. Ectopic fat depots within heart, liver, skeletal muscle, kidney, and pancreas …

Objective A branched-chain amino acid (BCAA)-related metabolic signature is strongly
associated with insulin resistance and predictive of incident diabetes and intervention …

Growth hormone (GH) is important for promotion of somatic growth and the regulation of
substrate metabolism. Metabolic action of GH occurs in multiple tissues including the liver …