Autophagy is an intracellular degradation system that maintains the stable state of cell
energy metabolism. Some recent findings have indicated that autophagy dysfunction is an …

Osteoarthritis (OA) is a degenerative disease that leads to joint pain and stiffness and is one
of the leading causes of disability and pain worldwide. Autophagy is a highly conserved self …

The pathophysiology of osteoarthritis (OA) is closely linked to autophagy abnormalities in
articular chondrocytes, the sole mature cell type in healthy cartilage. Nevertheless, the …

Osteoarthritis (OA) is a frequent chronic joint disease in orthopedics that effects individuals
and society significantly. Obesity, aging, genetic susceptibility, and joint misalignment are all …

Aberrant autophagic activity is observed in osteoarthritic joints. Vitamin D was shown to
alleviate not only osteoarthritis severity, but also autophagy process. However, the influence …

Infrapatellar fat pad (IPFP) inflammation is a common pathological manifestation in knee
osteoarthritis (OA). However, the significance of IPFP signal intensity alteration for clinical …

Background: Although osteoarthritis (OA) development is epidemiologically multifactorial, a
primary underlying mechanism is still under debate. Understanding the pathophysiology of …

This study uses the knee Osteoarthritis (OA) rat (constructed by the anterior cruciate
ligament transection) and the inflammatory chondrocyte (constructed by 20 ng mL− 1 tumor …

T-2 toxin could induce bone damage. But there is no specific mechanism about the long non-
coding RNAs (lncRNAs) involved in T-2 toxin-induced articular cartilage injury. In this study …

The risk factors of osteoarthritis (OA) are different and obesity, lifestyle, inflammation, cell
death mechanisms and diabetes mellitus are among them. The changes in the biological …