[PDF][PDF] Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses

DM Morens, JK Taubenberger, AS Fauci - Cell Host & Microbe, 2023 - cell.com
Viruses that replicate in the human respiratory mucosa without infecting systemically,
including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many other" …

T cell responses to SARS-CoV-2

A Sette, J Sidney, S Crotty - Annual review of immunology, 2023 - annualreviews.org
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses

T Mao, B Israelow, MA Peña-Hernández, A Suberi… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
highlighted the need for vaccines that not only prevent disease but also prevent …

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

YJ Park, D Pinto, AC Walls, Z Liu, A De Marco… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …

[HTML][HTML] SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+ and CD4+ T cells of broad specificity

JME Lim, AT Tan, N Le Bert, SK Hang… - Journal of Experimental …, 2022 - rupress.org
SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+
and CD4+ T cells of broad specificity | Journal of Experimental Medicine | Rockefeller …

SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic

A Bertoletti, N Le Bert, AT Tan - Immunity, 2022 - cell.com
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, multiple severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …

Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities—workshop report

JM Knisely, LE Buyon, R Mandt, R Farkas… - npj Vaccines, 2023 - nature.com
On November 7th and 8th, 2022, The National Institute of Allergy and Infectious Diseases
(NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic …

Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models

RL Hajnik, JA Plante, Y Liang, MG Alameh… - Science translational …, 2022 - science.org
Emergence of SARS-CoV-2 variants of concern (VOCs), including the highly transmissible
Omicron and Delta strains, has posed constant challenges to the current COVID-19 vaccines …

Operation nasal vaccine—lightning speed to counter COVID-19

EJ Topol, A Iwasaki - Science immunology, 2022 - science.org
Operation Nasal Vaccine—Lightning speed to counter COVID-19 | Science Immunology news
careers commentary Journals Science Science brought to you byGoogle Indexer Log in science …

Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8+ T cell responses post SARS-CoV-2 infection

F Gao, V Mallajosyula, PS Arunachalam… - Immunity, 2023 - cell.com
T cells are a critical component of the response to SARS-CoV-2, but their kinetics after
infection and vaccination are insufficiently understood. Using" spheromer" peptide-MHC …