[HTML][HTML] Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines

J Bilski, P Pierzchalski, M Szczepanik, J Bonior… - Cells, 2022 - mdpi.com
Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

[HTML][HTML] Vitamin D in osteosarcopenic obesity

L Di Filippo, R De Lorenzo, A Giustina… - Nutrients, 2022 - mdpi.com
Osteosarcopenic obesity is a unique clinical condition where low bone and muscle mass
coexist in individuals with obesity. Alterations in adipose tissue, skeletal muscle and bone …

[HTML][HTML] Sarcopenia as a comorbidity of cardiovascular disease

K Sasaki, Y Fukumoto - Journal of cardiology, 2022 - Elsevier
Sarcopenia, the lowered skeletal muscle mass, weakened skeletal muscle strength, and
reduced physical performance with aging, is a component of frailty and high-risk factor for …

[HTML][HTML] Obesity as a premature aging phenotype—implications for sarcopenic obesity

E Nunan, CL Wright, OA Semola, M Subramanian… - Geroscience, 2022 - Springer
Obesity and aging have both seen dramatic increases in prevalence throughout society.
This review seeks to highlight common pathologies that present with obesity, along with the …

Obesity paradox in aging: from prevalence to pathophysiology

S Wang, J Ren - Progress in cardiovascular diseases, 2018 - Elsevier
Recent advances in medical technology and health care have greatly improved the
management for chronic diseases and prolonged human lifespan. Unfortunately, increased …

[HTML][HTML] Osteosarcopenic obesity: current knowledge, revised identification criteria and treatment principles

OJ Kelly, JC Gilman, D Boschiero, JZ Ilich - Nutrients, 2019 - mdpi.com
Osteosarcopenic obesity (OSO) syndrome describes the simultaneous deterioration of bone,
muscle and excess fat, resulting in reduced functionality and systemic metabolic …

[HTML][HTML] Pathogenesis, intervention, and current status of drug development for sarcopenia: a review

JY Jang, D Kim, ND Kim - Biomedicines, 2023 - mdpi.com
Sarcopenia refers to the loss of muscle strength and mass in older individuals and is a major
determinant of fall risk and impaired ability to perform activities of daily living, often leading …

Sarcopenic obesity versus sarcopenia alone with the use of probable sarcopenia definition for sarcopenia: Associations with frailty and physical performance

S Ozkok, CO Aydin, DE Sacar, NM Catikkas, T Erdogan… - Clinical Nutrition, 2022 - Elsevier
Background & aims Ageing brings alterations in body composition, as skeletal muscle
gradually declines and accumulation of adipose tissue accompanies it. Although sarcopenia …

Global prevalence of osteosarcopenic obesity amongst middle aged and older adults: a systematic review and meta-analysis

Y Liu, Y Song, Q Hao, J Wu - Archives of Osteoporosis, 2023 - Springer
Purpose Osteosarcopenic obesity syndrome (OSO) is a recently recognized disorder
encompassing osteopenia/osteoporosis, sarcopenia, and obesity. However, evidence in …

[HTML][HTML] Is there enough evidence for osteosarcopenic obesity as a distinct entity? A critical literature review

JM Bauer, AJ Cruz-Jentoft, RA Fielding… - Calcified tissue …, 2019 - Springer
The co-existence of impaired bone health (osteopenia/osteoporosis), reduced muscle mass
and strength (sarcopenia), and increased adiposity (obesity) in middle-aged and older …