TWF1 induces autophagy and accelerates malignant phenotype in lung adenocarcinoma via inhibiting the cAMP signaling pathway

Y Wang, R Zuo, G Huo, Z Han, Y He, Y Luo… - The FASEB …, 2023 - Wiley Online Library
Many studies have shown that the actin cytoskeleton plays an essential role in the initiation
and progression of cancer. As an actin‐binding protein, Twinfilin1 (TWF1) plays an important …

[HTML][HTML] Resistance of lung cancer to EGFR-specific kinase inhibitors: activation of bypass pathways and endogenous mutators

I Marrocco, Y Yarden - Cancers, 2023 - mdpi.com
Simple Summary Genome-based cancer medicine is becoming the standard of care: the
patient's tumor DNA is first analyzed to identify driver mutations, and this permits later …

[HTML][HTML] Organometallic gold (I) and gold (III) complexes for lung cancer treatment

J Zhang, Y Li, R Fang, W Wei, Y Wang, J Jin… - Frontiers in …, 2022 - frontiersin.org
Metal compounds, especially gold complexes, have recently gained increasing attention as
possible lung cancer therapeutics. Some gold complexes display not only excellent activity …

Metformin increases the radiosensitivity of non-small cell lung cancer cells by destabilizing NRF2

X Sun, M Dong, Y Gao, Y Wang, L Du, Y Liu… - Biochemical …, 2022 - Elsevier
Radiation resistance is an obstacle to the successful treatment of lung cancer. Metformin, a
first-line antidiabetic drug, has been studied for its potential use in radiotherapy, as several …

[HTML][HTML] Cellular senescence in non-small cell lung cancer

H Zhu, J Sun, C Zhang, P Li, C Tan, M Yang… - Frontiers in Bioscience …, 2023 - imrpress.com
Lung cancer has the highest mortality rate amongst all malignancies worldwide, and is the
second-highest incidence of cancer in women. Non-small cell lung cancer (NSCLC) is …

[HTML][HTML] RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway

X Ding, X Li, Y Jiang, Y Li, H Li, L Shang, G Feng… - Cancer Cell …, 2024 - Springer
Background Novel therapeutic targets are urgently needed for treating drug-resistant non-
small cell lung cancer (NSCLC) and overcoming drug resistance to molecular-targeted …

Optimization of capillary electrophoresis coupled to negative mode electrospray ionization-mass spectrometry using polyvinyl alcohol coated capillaries. Application to …

Á López-López, M Ciborowski, J Niklinski… - Analytica Chimica …, 2022 - Elsevier
Despite recent developments in separation techniques, the analysis of relatively small highly
polar negatively charged analytes (eg small organic acids, phosphorylated sugars, and …

[HTML][HTML] Efficacy and safety assessment of intrathoracic perfusion chemotherapy combined with immunological factor interleukin-2 in the treatment of advanced non …

Q Cao, J Zhu, X Wu, J Li, Y Chen, Y You, X Li… - Journal of …, 2024 - ncbi.nlm.nih.gov
Objective: This study evaluated the efficacy and safety of the gemcitabine and oxaliplatin
intrathoracic perfusion chemotherapy (IPCGOR) regimen combined with interleukin-2 (IL-2) …

[HTML][HTML] Determination of osimertinib, aumolertinib, and furmonertinib in human plasma for therapeutic drug monitoring by UPLC-MS/MS

Y Li, L Meng, Y Ma, Y Li, X Xing, C Guo, Z Dong - Molecules, 2022 - mdpi.com
The third-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-
TKIs), osimertinib, aumolertinib, and furmonertinib represent a new treatment option for …

Fast proliferating and slowly migrating non‐small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment

G Pelos, M Riester, J Pal, K Myacheva… - … Journal of Cancer, 2024 - Wiley Online Library
Non‐small cell lung cancer (NSCLC) patients are often elderly or unfit and thus cannot
tolerate standard aggressive therapy regimes. In our study, we test the efficacy of the DNA …