Acute complications such as veno-occlusive disease of the liver, acute and chronic graft-vs-
host disease (GVHD), and infectious conditions remain major obstacles for the success of …

Reports from more than 600 hematopoietic stem cell transplants (HSCT) have appeared in
the medical literature for the last 1 and one-half decades. The patient's own stem cells are …

Background: Controlled trials in lupus nephritis have demonstrated that cyclophosphamide
therapy is superior to corticosteroid therapy alone. The long-term effectiveness and side …

ContextManifestations of systemic lupus erythematosus (SLE) may in most patients be
ameliorated with medications that suppress the immune system. Nevertheless, there …

Administration of donor T cells expressing the herpes simplex–thymidine kinase (HS-tk) with
a hematopoietic stem cell (HSC) transplantation could allow, if graft-versus-host disease …

BACKGROUND AND OBJECTIVE: Although biphenotypic leukemia is now a defined entity,
outcome of this rare form of acute leukemia has not been well documented. We present the …

Intractable autoimmune diseases in chimeric resistant MRL/lpr mice were treated by a new
bone marrow transplantation (BMT) method consisting of fractionated irradiation, 5.5 Gy× 2 …

This ongoing multicentre prospective phase I/II trial enrolled 74 consecutive patients from 22
centres worldwide with severe autoimmune disease, 35 with rheumatological disorders, 31 …

Based on the good results of experimental transplantation in animal models of multiple
sclerosis and of other autoimmune diseases, we have treated 24 patients suffering from …

We reviewed data from 24 transplant centers in Asia, Australia, Europe, and North America
to determine the outcomes of stem cell collection including methods used, cell yields, effects …