We have presented and/or briefly reviewed data which indicates that there are two T cell
subsets which interact respectively with the two Classes (1 and 2) of MHC antigen and …

We describe here the properties of mAb GK1. 5, which recognizes a cell surface molecule
designated L3T4; the determinant on L3T4 recognized by mAb GK1. 5 is designated L3T4a …

Monoclonal antibodies (MAb) have been used to probe the relationship of cytolytic T
lymphocyte (CTL) surface molecules to CTL function. Rat MAb to mouse CTL were …

Mouse Mac-1, a complement receptor-associated surface structure on macrophages, and
LFA-1, a function-associated structure on lymphocytes, comprise a novel family of leukocyte …

During T cell development, precursor thymocytes that co‐express the CD4 and CD8
glycoproteins give rise to mature progeny expressing one of these molecules to the …

The monoclonal antibody methodology was used to identify membrane structures involved
in T cell functions. To optimize chances to produce and detect relevant antibodies, a …

The T cell receptor α and β chain genes donated by an H-2 class I-specific, CD8-dependent
cytotoxic T cell clone were transferred, alone or in combination with the Lyt-2 gene, into a …

Adhesions of lymphocytes, among themselves or with other cell types, are necessary for
most steps in immune responses including both induction and effector phases. Among …

Out of a panel of seven monoclonal antibodies with affinity for human lymphoid cells, three
were shown to prevent cytotoxic T cell activity, whereas none affected natural killer cell …

The central theme of this work has been the roles of the CTL receptor and of MHC-proteins
in CTL recognition and lysis. A major conclusion that may be deduced from the work …