[HTML][HTML] Nanomedicine and epigenome. Possible health risks
B Smolkova, M Dusinska, A Gabelova - Food and Chemical Toxicology, 2017 - Elsevier
Nanomedicine is an emerging field that combines knowledge of nanotechnology and
material science with pharmaceutical and biomedical sciences, aiming to develop …
material science with pharmaceutical and biomedical sciences, aiming to develop …
[HTML][HTML] Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4
DNA methylation is implicated in the acquisition of malignant phenotypes, and the use of
epigenetic modulating drugs is a promising anti-cancer therapeutic strategy. 5-aza …
epigenetic modulating drugs is a promising anti-cancer therapeutic strategy. 5-aza …
[HTML][HTML] Stress and the emerging roles of chromatin remodeling in signal integration and stable transmission of reversible phenotypes
ICG Weaver, AC Korgan, K Lee, RV Wheeler… - Frontiers in Behavioral …, 2017 - frontiersin.org
The influence of early life experience and degree of parental-infant attachment on emotional
development in children and adolescents has been comprehensively studied. Structural and …
development in children and adolescents has been comprehensively studied. Structural and …
Neurodegenerative movement disorders: An epigenetics perspective and promise for the future
M Murthy, YY Cheng, JL Holton… - Neuropathology and …, 2021 - Wiley Online Library
Neurodegenerative movement disorders (NMDs) are age‐dependent disorders that are
characterised by the degeneration and loss of neurons, typically accompanied by …
characterised by the degeneration and loss of neurons, typically accompanied by …
Artificial intelligence for dementia genetics and omics
Genetics and omics studies of Alzheimer's disease and other dementia subtypes enhance
our understanding of underlying mechanisms and pathways that can be targeted. We …
our understanding of underlying mechanisms and pathways that can be targeted. We …
[HTML][HTML] Ageing in the brain: mechanisms and rejuvenating strategies
F Gaspar-Silva, D Trigo, J Magalhaes - Cellular and Molecular Life …, 2023 - Springer
Ageing is characterized by the progressive loss of cellular homeostasis, leading to an
overall decline of the organism's fitness. In the brain, ageing is highly associated with …
overall decline of the organism's fitness. In the brain, ageing is highly associated with …
From 1D sequence to 3D chromatin dynamics and cellular functions: a phase separation perspective
S Liu, L Zhang, H Quan, H Tian, L Meng… - Nucleic acids …, 2018 - academic.oup.com
The high-order chromatin structure plays a non-negligible role in gene regulation. However,
the mechanism, especially the sequence dependence for the formation of varied chromatin …
the mechanism, especially the sequence dependence for the formation of varied chromatin …
Shared mechanisms among neurodegenerative diseases: from genetic factors to gene networks
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis are pressing health concerns in modern societies for which …
amyotrophic lateral sclerosis are pressing health concerns in modern societies for which …
[HTML][HTML] Panoramic visualization of circulating microRNAs across neurodegenerative diseases in humans
Neurodegenerative diseases (NDs) such as Alzheimer's disease (AD), Parkinson's disease
(PD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and dementia pose one of …
(PD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and dementia pose one of …
Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by …
R Marin, N Fabelo, V Martín, P Garcia-Esparcia… - Neurobiology of …, 2017 - Elsevier
Lipid rafts are highly dynamic membrane microdomains intimately associated with cell
signaling. Compelling evidence has demonstrated that alterations in lipid rafts are …
signaling. Compelling evidence has demonstrated that alterations in lipid rafts are …