[HTML][HTML] Nanomedicine and epigenome. Possible health risks

B Smolkova, M Dusinska, A Gabelova - Food and Chemical Toxicology, 2017 - Elsevier
Nanomedicine is an emerging field that combines knowledge of nanotechnology and
material science with pharmaceutical and biomedical sciences, aiming to develop …

[HTML][HTML] Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4

M Vernier, S McGuirk, CR Dufour, L Wan… - Oncogene, 2020 - nature.com
DNA methylation is implicated in the acquisition of malignant phenotypes, and the use of
epigenetic modulating drugs is a promising anti-cancer therapeutic strategy. 5-aza …

[HTML][HTML] Stress and the emerging roles of chromatin remodeling in signal integration and stable transmission of reversible phenotypes

ICG Weaver, AC Korgan, K Lee, RV Wheeler… - Frontiers in Behavioral …, 2017 - frontiersin.org
The influence of early life experience and degree of parental-infant attachment on emotional
development in children and adolescents has been comprehensively studied. Structural and …

Neurodegenerative movement disorders: An epigenetics perspective and promise for the future

M Murthy, YY Cheng, JL Holton… - Neuropathology and …, 2021 - Wiley Online Library
Neurodegenerative movement disorders (NMDs) are age‐dependent disorders that are
characterised by the degeneration and loss of neurons, typically accompanied by …

Artificial intelligence for dementia genetics and omics

C Bettencourt, N Skene, S Bandres‐Ciga… - Alzheimer's & …, 2023 - Wiley Online Library
Genetics and omics studies of Alzheimer's disease and other dementia subtypes enhance
our understanding of underlying mechanisms and pathways that can be targeted. We …

[HTML][HTML] Ageing in the brain: mechanisms and rejuvenating strategies

F Gaspar-Silva, D Trigo, J Magalhaes - Cellular and Molecular Life …, 2023 - Springer
Ageing is characterized by the progressive loss of cellular homeostasis, leading to an
overall decline of the organism's fitness. In the brain, ageing is highly associated with …

From 1D sequence to 3D chromatin dynamics and cellular functions: a phase separation perspective

S Liu, L Zhang, H Quan, H Tian, L Meng… - Nucleic acids …, 2018 - academic.oup.com
The high-order chromatin structure plays a non-negligible role in gene regulation. However,
the mechanism, especially the sequence dependence for the formation of varied chromatin …

Shared mechanisms among neurodegenerative diseases: from genetic factors to gene networks

D Arneson, Y Zhang, X Yang, M Narayanan - Journal of genetics, 2018 - Springer
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis are pressing health concerns in modern societies for which …

[HTML][HTML] Panoramic visualization of circulating microRNAs across neurodegenerative diseases in humans

S Brennan, M Keon, B Liu, Z Su, NK Saksena - Molecular neurobiology, 2019 - Springer
Neurodegenerative diseases (NDs) such as Alzheimer's disease (AD), Parkinson's disease
(PD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and dementia pose one of …

Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by …

R Marin, N Fabelo, V Martín, P Garcia-Esparcia… - Neurobiology of …, 2017 - Elsevier
Lipid rafts are highly dynamic membrane microdomains intimately associated with cell
signaling. Compelling evidence has demonstrated that alterations in lipid rafts are …