CB1-and CB2-type cannabinoid receptors mediate effects of the endocannabinoids 2-
arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid …

The actions of cannabis are mediated by G protein-coupled receptors that are part of an
endogenous cannabinoid system (ECS). ECS consists of the naturally occurring ligands N …

The neurobiological mechanisms underlying the effects of delta-9-tetrahydrocannabinol
(THC) remain unclear. Here, we examined the spatial acute effect of THC on human on …

The cannabinoid receptor (CB1) was studied primarily in mammals where it was found to
comprise a link between reward processes and addictive behavior such as food …

The endocannabinoids (ECBs) have diverse physiological functions including the regulation
of food intake and metabolism. In mammals, ECBs regulate feeding primarily through the …

Abstract Cannabinoid CB1 receptors (CB1R) are widely distributed in the brains of many
vertebrates, but whether their functions are conserved is unknown. The weakly electric fish …

OBJECTIVE To determine the pharmacokinetics of 8 cannabinoids and 5 metabolites after
oral administration of single and multiple doses of a cannabidiol (CBD)-cannabidiolic acid …

Alcohol consumption is mediated by several important neuromodulatory systems, including
the endocannabinoid and neuropeptide Y (NPY) systems in the limbic brain circuitry …

Fast, temporally-precise, and consistent synaptic transmission is required to encode features
of acoustic stimuli. Neurons of nucleus magnocellularis (NM) in the auditory brain stem of …

This chapter addresses the discriminative stimulus (DS) functions of agents that primarily
affect what is commonly known today as the endocannabinoid signaling system (ECS). Drug …