Haemodialysis (HD) is the commonest form of kidney replacement therapy in the world,
accounting for approximately 69% of all kidney replacement therapy and 89% of all dialysis …

Opioid abuse and addiction have become a global pandemic, posing tremendous health
and social burdens. The rewarding effects and the occurrence of withdrawal symptoms are …

The US is grappling with an opioid epidemic, with millions of adults on long-term opioid
therapy (LTOT). Although patients often report pain relief and improved daily function with …

Chronic kidney disease patients undergoing hemodialysis, experience a high burden of
functional disorders, limited life expectancy, health services, complications that cause …

Background Chronic pain is prevalent but difficult to treat in patients undergoing
hemodialysis (HD). Effective and safe analgesics are limited in this patient population. Our …

Objective The objective of this review is to conduct a comprehensive and systematic
assessment of the efficacy of Yoga as an intervention for knee osteoarthritis (KOA). Methods …

Activation of opioid receptors in the anterior cingulate cortex (ACC) mediates aspects of
analgesia induced by both exogenous and endogenous opioids. We have previously shown …

Many kidney transplant recipients continue to experience high symptom burden despite
restoration of kidney function. High symptom burden is a significant driver of quality of life. In …

Protein-energy wasting (PEW) denotes the pathologic combination of undernutrition and
excessive catabolism observed mainly in patients with chronic kidney disease (CKD). The …

Background: Although osteoarthritis is common in the hemodialysis population and leads to
poor health outcomes, pain management is challenged by the absence of clinical guidance …