Leaving flatland: Advances in 3D behavioral measurement

JD Marshall, T Li, JH Wu, TW Dunn - Current Opinion in Neurobiology, 2022 - Elsevier
Animals move in three dimensions (3D). Thus, 3D measurement is necessary to report the
true kinematics of animal movement. Existing 3D measurement techniques draw on …

Brain repair mechanisms after cell therapy for stroke

R Rust, LR Nih, L Liberale, H Yin, M El Amki, LK Ong… - Brain, 2024 - academic.oup.com
Cell-based therapies hold great promise for brain repair after stroke. While accumulating
evidence confirms the preclinical and clinical benefits of cell therapies, the underlying …

Smartphone video nystagmography using convolutional neural networks: ConVNG

MU Friedrich, E Schneider, M Buerklein, J Taeger… - Journal of …, 2023 - Springer
Background Eye movement abnormalities are commonplace in neurological disorders.
However, unaided eye movement assessments lack granularity. Although videooculography …

Stem cell therapy for repair of the injured brain: Five principles

R Rust, C Tackenberg - The Neuroscientist, 2024 - journals.sagepub.com
Cell therapy holds great promise for regenerative treatment of disease. Despite recent
breakthroughs in clinical research, applications of cell therapies to the injured brain have not …

[HTML][HTML] A toolkit for stroke infarct volume estimation in rodents

RZ Weber, D Bernardoni, NH Rentsch, BA Buil… - Neuroimage, 2024 - Elsevier
Stroke volume is a key determinant of infarct severity and an important metric for evaluating
treatments. However, accurate estimation of stroke volume can be challenging, due to the …

Application of multiple-finding segmentation utilizing Mask R-CNN-based deep learning in a rat model of drug-induced liver injury

EB Baek, J Lee, JH Hwang, H Park, BS Lee, YB Kim… - Scientific Reports, 2023 - nature.com
Drug-induced liver injury (DILI) presents significant diagnostic challenges, and recently
artificial intelligence-based deep learning technology has been used to predict various …

Molecular and anatomical roadmap of stroke pathology in immunodeficient mice

RZ Weber, G Mulders, P Perron, C Tackenberg… - Frontiers in …, 2022 - frontiersin.org
Background Stroke remains a leading cause of disability and death worldwide. It has
become apparent that inflammation and immune mediators have a pre-dominant role in …

Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications

R Rust, RZ Weber, M Generali, D Kehl… - Journal of Translational …, 2022 - Springer
Background Currently, there is no regenerative therapy for patients with neurological and
neurodegenerative disorders. Cell-therapies have emerged as a potential treatment for …

Preserving stroke penumbra by targeting lipid signalling

B Achón Buil, R Rust - Journal of Cerebral Blood Flow & …, 2023 - journals.sagepub.com
Preserving stroke penumbra by targeting lipid signalling - Beatriz Achón Buil, Ruslan Rust,
2023 Skip to main content Intended for healthcare professionals Sage Journals Home Search …

[HTML][HTML] From rodents to humans: Rodent behavioral paradigms for social behavioral disorders

M Guo, L Sun - Brain Circulation, 2023 - journals.lww.com
Social cognition guides social behavior. Subjects with proper social cognition should be
able to:(1) have reasonable social motivation,(2) recognize other people and infer their …