Human papillomavirus epidemiology and prevention: is there still a gender gap?

G Milano, G Guarducci, N Nante, E Montomoli, I Manini - Vaccines, 2023 - mdpi.com
Background and aim: Human papillomavirus (HPV) is sexually transmitted, one of the three
most common sexually transmitted infections (STIs) in both males and females, and the most …

Polyfunctional antibodies: a path towards precision vaccines for vulnerable populations

RA Purcell, RM Theisen, KB Arnold… - Frontiers in …, 2023 - frontiersin.org
Vaccine efficacy determined within the controlled environment of a clinical trial is usually
substantially greater than real-world vaccine effectiveness. Typically, this results from …

Head-to-head immunogenicity comparison of an Escherichia coli-produced 9-valent human papillomavirus vaccine and Gardasil 9 in women aged 18–26 years in …

FC Zhu, GH Zhong, WJ Huang, K Chu… - The Lancet Infectious …, 2023 - thelancet.com
Summary Background An Escherichia coli-produced human papillomavirus (HPV) 16 and
18 bivalent vaccine (Cecolin) was prequalified by WHO in 2021. This study aimed to …

[HTML][HTML] Immunogenicity and safety of an Escherichia coli-produced human papillomavirus (types 6/11/16/18/31/33/45/52/58) L1 virus-like-particle vaccine: a phase 2 …

YM Hu, ZF Bi, Y Zheng, L Zhang, FZ Zheng, K Chu… - Science Bulletin, 2023 - Elsevier
The Escherichia coli-produced human papillomavirus (HPV) 16/18 bivalent vaccine
(Cecolin) has received prequalification by the World Health Organization based on its high …

HPV natural history, immunological responses and vaccination strategies: challenges and opportunities

ZQ Toh, F Zhao, L Zhang, L Wei, H Zou - Frontiers in Immunology, 2024 - frontiersin.org
Human papillomavirus (HPV) infection is the most common sexually transmitted infection,
with up to 90% of individuals infected with HPV at some point in their lives (1). While most …

Lack of detectable HPV18 antibodies in 14% of quadrivalent vaccinees in a longitudinal cohort study

P Gray, FC Mariz, C Eklund, T Eriksson, H Faust… - npj Vaccines, 2024 - nature.com
Although HPV vaccines are highly efficacious, a notable proportion of quadrivalent
vaccinees are HPV18 seronegative post-vaccination. We have investigated this findings' …

Unveiling the seroprevalence of human papillomavirus in Guangdong, China: Implications for vaccination strategies

X Hu, Y Chen, W Lin, Q Ruan, H Chen… - Journal of Medical …, 2024 - Wiley Online Library
Seroepidemiological characteristics of human papillomavirus (HPV) in community residents
reflect natural infection and can guide the reform of vaccination programs. A population …

Beyond bNAbs: Uses, Risks, and Opportunities for Therapeutic Application of Non-Neutralising Antibodies in Viral Infection

K Mader, LB Dustin - Antibodies, 2024 - mdpi.com
The vast majority of antibodies generated against a virus will be non-neutralising. However,
this does not denote an absence of protective capacity. Yet, within the field, there is typically …

[HTML][HTML] The Clinical Effectiveness of Single-Dose Human Papillomavirus Vaccination

W Bao, X He, Y Huang, R Liu, Z Li - Vaccines, 2024 - mdpi.com
The human papillomavirus (HPV) vaccine was initially approved for a three-dose regimen.
Due to resource limitations, budget constraints, low acceptance, and poor adherence, global …

Development of a human papillomavirus (HPV) multiplex immunoassay to profile HPV antibodies

C Quang, AW Chung, TJ Kemp, T Ratu… - Journal of Medical …, 2024 - Wiley Online Library
Neutralizing antibodies (NAbs) are considered the primary mechanism of vaccine‐mediated
protection against human papillomaviruses (HPV), the causative agent of cervical cancer …