Nanomedicine against malaria

P Urban, X Fernandez-Busquets - Current Medicinal Chemistry, 2014 - ingentaconnect.com
Malaria is arguably one of the main medical concerns worldwide because of the numbers of
people affected, the severity of the disease and the complexity of the life cycle of its …

Synthesis of the new analogs of morpholine and their antiplasmodial evaluation against the human malaria parasite Plasmodium falciparum

C Upadhyay, N Sharma, S Kumar, PP Sharma… - New Journal of …, 2022 - pubs.rsc.org
A series of morpholine analogs functionalized with hydroxyethylamine (HEA)
pharmacophore was synthesized and assayed for the initial screening against Plasmodium …

Infection of mother and baby

CRR George, HE Jeffery, MM Lahra - Keeling's Fetal and Neonatal …, 2022 - Springer
Infection in pregnancy is associated with pre term birth, intra uterine death and transmission
of infection to the fetus and neonate. Common infections such as urinary tract, respiratory …

[HTML][HTML] Improving neuropharmacology using big data, machine learning and computational algorithms

K Shameer, A Nayarisseri, FXR Duran… - Current …, 2017 - ncbi.nlm.nih.gov
Drugs perform dynamic role in perturbing the functional phenotypes of organism; for
example, a drug with the vasorelaxant role may have an impact on the nervous system …

Development of drug-loaded immunoliposomes for the selective targeting and elimination of rosetting Plasmodium falciparum-infected red blood cells

E Moles, K Moll, JH Ch'ng, P Parini, M Wahlgren… - Journal of Controlled …, 2016 - Elsevier
Parasite proteins exported to the surface of Plasmodium falciparum-parasitized red blood
cells (pRBCs) have a major role in severe malaria clinical manifestation, where pRBC …

Plasmodium falciparum malaria occurring 8 years after leaving an endemic area

PE Szmitko, ML Kohn, AE Simor - Diagnostic microbiology and infectious …, 2009 - Elsevier
A 29-year-old patient who was born in Angola developed Plasmodium falciparum malaria 8
years after leaving Africa. She had not returned to a malaria-endemic area, and there were …

An overview of currently available antimalarials

N Yu Gorobets, YV Sedash, BK Singh… - Current topics in …, 2017 - ingentaconnect.com
Background: Despite the substantial progress over the time, malaria remains a major public
health concern and causing hundreds of thousands of deaths. Resistance to the available …

[HTML][HTML] Plasmodium species and drug resistance

ST Tseha - Plasmodium species and drug resistance, 2021 - intechopen.com
Malaria is a leading public health problem in tropical and subtropical countries of the world.
In 2019, there were an estimated 229 million malaria cases and 409, 000 deaths due …

[HTML][HTML] Repurposing heparin as antimalarial: Evaluation of multiple modifications toward In Vivo application

E Lantero, CR Aláez-Versón, P Romero, T Sierra… - Pharmaceutics, 2020 - mdpi.com
Heparin is a promising antimalarial drug due to its activity in inhibiting Plasmodium invasion
of red blood cells and to the lack of resistance evolution by the parasite against it, but its …

[HTML][HTML] Antiplasmodial activity of the andiroba (Carapa guianensis Aubl., Meliaceae) oil and its limonoid-rich fraction

RNCM Júnior, MF Dolabela, MN da Silva… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: From seeds of Carapa guianensis the Amazon
native people extracts the andiroba oil, which is traditionally used as febrifuge, anti-malarial …