Triggering and resolution of inflammation in NASH

S Schuster, D Cabrera, M Arrese… - Nature reviews …, 2018 - nature.com
Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …

[HTML][HTML] Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism

S Lefere, F Tacke - JHEP reports, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide, and
a major cause of liver cirrhosis and hepatocellular carcinoma. NAFLD is intimately linked …

[PDF][PDF] Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis

H Gao, Z Jin, G Bandyopadhyay, G Wang, D Zhang… - Cell metabolism, 2022 - cell.com
Hepatocytes have important roles in liver iron homeostasis, abnormalities in which are
tightly associated with liver steatosis and fibrosis. Here, we show that non-alcoholic fatty liver …

Oxidative stress in NAFLD: role of nutrients and food contaminants

C Rives, A Fougerat, S Ellero-Simatos, N Loiseau… - Biomolecules, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …

Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver …

S McPherson, MJ Armstrong, JF Cobbold… - The lancet …, 2022 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) is common, affecting approximately 25% of the
general population. The evidence base for the investigation and management of NAFLD is …

[HTML][HTML] Iron and liver fibrosis: Mechanistic and clinical aspects

KJ Mehta, SJ Farnaud, PA Sharp - World journal of …, 2019 - ncbi.nlm.nih.gov
Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts
normal liver functionality. It is a pathological stage in several untreated chronic liver …

Gut microbiota bridges the iron homeostasis and host health

L Xiao, R Tang, J Wang, D Wan, Y Yin, L Xie - Science China Life …, 2023 - Springer
The gut microbiota acts as a symbiotic microecosystem that plays an indispensable role in
the regulation of a number of metabolic processes in the host by secreting secondary …

Ferroptosis and metabolic dysfunction‐associated fatty liver disease: Is there a link?

G Feng, CD Byrne, G Targher, F Wang… - Liver …, 2022 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD), recently re‐defined and re‐classified as
metabolic dysfunction‐associated fatty liver disease (MAFLD), has become increasingly …

Iron regulatory protein 1 promotes ferroptosis by sustaining cellular iron homeostasis in melanoma

F Yao, X Cui, Y Zhang, Z Bei, H Wang… - Oncology …, 2021 - spandidos-publications.com
Melanoma, the most aggressive skin cancer, is mainly treated with BRAF inhibitors or
immunotheareapy. However, most patients who initially responded to BRAF inhibitors or …

Targeting programmed cell death in metabolic dysfunction-associated fatty liver disease (MAFLD): a promising new therapy

J Zhao, Y Hu, J Peng - Cellular & Molecular Biology Letters, 2021 - Springer
Most currently recommended therapies for metabolic dysfunction-associated fatty liver
disease (MAFLD) involve diet control and exercise therapy. We searched PubMed and …