Iron deficiency during the first 1000 days of life: are we doing enough to protect the developing brain?

EK McCarthy, DM Murray, ME Kiely - Proceedings of the Nutrition …, 2022 - cambridge.org
Iron is essential for the functioning of all cells and organs, most critically for the developing
brain in the fundamental neuronal processes of myelination, energy and neurotransmitter …

A literature review of evidence for primary prevention of overweight and obesity in healthy weight children and adolescents: a report produced by a working group of …

NJ Olsen, JN Østergaard, LG Bjerregaard… - Obesity …, 2024 - Wiley Online Library
Primary prevention targets development of overweight in individuals with healthy weight and
is a great challenge. This paper summarizes the main findings of a working group of the …

[HTML][HTML] App-supported lifestyle interventions in pregnancy to manage gestational weight gain and prevent gestational diabetes: scoping review

R Raab, K Geyer, S Zagar, H Hauner - Journal of Medical Internet Research, 2023 - jmir.org
Background Excessive gestational weight gain (GWG) and gestational diabetes mellitus
(GDM) are common pregnancy complications that have been shown to be preventable …

Maternal pre-pregnancy body mass index is associated with newborn offspring hypothalamic mean diffusivity: a prospective dual-cohort study

JM Rasmussen, JJ Tuulari, S Nolvi, PM Thompson… - BMC medicine, 2023 - Springer
Background An extensive body of animal literature supports the premise that maternal
obesity during pregnancy can alter the development of the fetal hypothalamus (HTH, a …

Maternal cardiovascular disorders before and during pregnancy and offspring cardiovascular risk across the life course

R Gaillard, VWV Jaddoe - Nature Reviews Cardiology, 2023 - nature.com
Obesity, hypertension, type 2 diabetes mellitus and dyslipidaemia are highly prevalent
among women of reproductive age and contribute to complications in> 30% of pregnancies …

Obesity downregulates lipid metabolism genes in first trimester placenta

A Rasool, T Mahmoud, B Mathyk, T Kaneko-Tarui… - Scientific Reports, 2022 - nature.com
Placentas of obese women have low mitochondrial β-oxidation of fatty acids (FA) and
accumulate lipids in late pregnancy. This creates a lipotoxic environment, impairing …

The uterine environment and childhood obesity risk: mechanisms and predictions

A Cristian, JL Tarry-Adkins, CE Aiken - Current Nutrition Reports, 2023 - Springer
Abstract Purpose of Review Childhood obesity is a growing health problem in many
populations, hence the urgent need to unravel the underlying mechanisms. Some evidence …

Maternal overweight and obesity during pregnancy: strategies to improve outcomes for women, babies, and children

JM Dodd, AR Deussen, M Mitchell… - Expert Review of …, 2022 - Taylor & Francis
Introduction Women with overweight and obesity, and their children, are at increased risk of
adverse pregnancy, birth, and longer term health outcomes, believed to be compounded by …

Maternal pea fiber supplementation to a high calorie diet in obese pregnancies protects male offspring from metabolic dysfunction in adulthood

GA Andreani, S Mahmood, MS Patel… - … Origins of Health and …, 2023 - cambridge.org
We investigated the influence of maternal yellow-pea fiber supplementation in obese
pregnancies on offspring metabolic health in adulthood. Sixty newly-weaned female …

Childhood follow‐up of the GRoW randomized trial: Metformin in addition to dietary and lifestyle advice for pregnant women with overweight or obesity

AR Deussen, J Louise, JM Dodd - Pediatric Obesity, 2023 - Wiley Online Library
Background Metformin for women with overweight or obesity during pregnancy has been
evaluated in randomized trials to reduce adverse pregnancy and birth outcomes. The effect …