Expression of Raf kinase inhibitor protein is downregulated in response to Newcastle disease virus infection to promote viral replication
R Yin, X Liu, Y Bi, G Xie, P Zhang… - Journal of General …, 2015 - microbiologyresearch.org
Newcastle disease virus (NDV) causes a severe and economically significant disease
affecting almost the entire poultry industry worldwide. However, factors that affect NDV …
affecting almost the entire poultry industry worldwide. However, factors that affect NDV …
[HTML][HTML] Stemness-associated markers are expressed in extracranial arteriovenous malformation
CS Luke Krishnan, HD Brasch, J Patel, N Bockett… - Frontiers in …, 2021 - frontiersin.org
Objectives: Arteriovenous malformation (AVM) consists of a nidus with poorly formed low-
resistance vessels in place of a functional capillary network. The role of somatic mutations in …
resistance vessels in place of a functional capillary network. The role of somatic mutations in …
Prediction of human pharmacokinetics of ulixertinib, a novel ERK1/2 inhibitor from mice, rats, and dogs pharmacokinetics
PS Suresh, RK Jairam, DV Chandrasekhar… - European Journal of …, 2018 - Springer
Abstract Background and Objectives Ulixertinib (BVD-523) is a novel and selective
reversible inhibitor of ERK1/ERK2. The primary objectives of the study were to evaluate the …
reversible inhibitor of ERK1/ERK2. The primary objectives of the study were to evaluate the …
Targeted therapies in melanoma
SJ Moschos, R Pinnamaneni - Surgical Oncology Clinics, 2015 - surgonc.theclinics.com
Similar to those for other cancers, targeted therapies for malignant melanoma (MM) have
only been under investigation for a little more than a decade. Before 2010, treatment of MM …
only been under investigation for a little more than a decade. Before 2010, treatment of MM …
Therapeutic interventions to disrupt the protein synthetic machinery in melanoma
GR Kardos, GP Robertson - Pigment cell & melanoma research, 2015 - Wiley Online Library
Control of the protein synthetic machinery is deregulated in many cancers, including
melanoma, to increase the protein production. Tumor suppressors and oncogenes play key …
melanoma, to increase the protein production. Tumor suppressors and oncogenes play key …
Dual inhibition of SHP2 and autophagy suppresses NF1-associated Malignant Peripheral Nerve Sheath Tumors
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas and the
primary cause of mortality in patients with neurofibromatosis type 1 (NF1). MPNSTs develop …
primary cause of mortality in patients with neurofibromatosis type 1 (NF1). MPNSTs develop …
The mTOR signaling pathway is associated with the prognosis of malignant pleural mesothelioma after multimodality therapy
A Kuroda, S Matsumoto, A Fukuda… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: We performed multimodality therapy comprising preoperative
chemotherapy, extrapleural pneumonectomy (EPP), and radiation therapy for patients with …
chemotherapy, extrapleural pneumonectomy (EPP), and radiation therapy for patients with …
Mécanismes de résistance aux inhibiteurs de protéines à bromodomaine et domaine extra-terminale dans l'ostéosarcome
L Marchandet - 2022 - theses.hal.science
L'ostéosarcome (OS) est une tumeur osseuse primaire agressive qui touche principalement
les enfants et les jeunes adultes, avec un pic d'incidence à 18 ans. La survie à long terme …
les enfants et les jeunes adultes, avec un pic d'incidence à 18 ans. La survie à long terme …