Chemokines are key players in the attraction and activation of leukocytes and are thus
implicated in the recruitment of immune cells at sites of infection and/or inflammation. They …

Stem/progenitor cells can be used to repair defects in the airway wall, resulting from eg,
tumors, trauma, tissue reactions following long-time intubations, or diseases that are …

T cells must migrate in order to encounter antigen-presenting cells (APCs) and to execute
their varied functions in immune defense and inflammation. ATP release and autocrine …

Chronic rejection is the major leading cause of morbidity and mortality after lung
transplantation. Bronchiolitis obliterans syndrome (BOS), a fibroproliferative disorder of the …

Background The mechanisms regulating CD8+ T cell migration to nonlymphoid tissue
during inflammation have not been fully elucidated, and the migratory properties of effector …

Chronic lung allograft dysfunction (CLAD) limits long-term survival after lung transplant (LT).
Ischemia–reperfusion injury (IRI) promotes chronic rejection (CR) and CLAD, but the …

Mesenchymal stem cells (MSCs) are thought to have great potential in the therapy of acute
liver injury. It is possible that these cells may be regulated by the stromal cell-derived factor …

OBJECTIVES The CD26 antigen is a transmembrane glycoprotein that is constitutively
expressed on activated lymphocytes and in pulmonary parenchyma. This molecule is also …

Aging is a natural process characterized by a progressive functional impairment and
reduced capacity to respond adaptively to environmental stimuli. Aging is associated with …

The chemokine receptor CXCR4 and its chemokine CXCL12 are involved in normal tissue
patterning but also in tumor cell growth and survival as well as in the recruitment of immune …