Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function

A Quarteroni, T Lassila, S Rossi… - Computer Methods in …, 2017 - Elsevier
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …

A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

M Fedele, E Faggiano, L Dedè, A Quarteroni - Biomechanics and modeling …, 2017 - Springer
In this paper, we propose a full computational framework to simulate the hemodynamics in
the aorta including the valve. Closed and open valve surfaces, as well as the lumen aorta …

Fluid dynamics of an idealized left ventricle: the extended Nitsche's method for the treatment of heart valves as mixed time varying boundary conditions

A Tagliabue, L Dede… - International Journal for …, 2017 - Wiley Online Library
In this work, we study the blood flow dynamics in idealized left ventricles (LV) of the human
heart modelled by the Navier–Stokes equations with mixed time varying boundary …

Complex blood flow patterns in an idealized left ventricle: a numerical study

A Tagliabue, L Dedè, A Quarteroni - Chaos: An Interdisciplinary …, 2017 - pubs.aip.org
In this paper, we study the blood flow dynamics in a three-dimensional (3D) idealized left
ventricle of the human heart whose deformation is driven by muscle contraction and …

[HTML][HTML] A parametric geometry model of the aortic valve for subject-specific blood flow simulations using a resistive approach

G Pase, E Brinkhuis, T De Vries, J Kosinka… - … and Modeling in …, 2023 - Springer
Cardiac valves simulation is one of the most complex tasks in cardiovascular modeling.
Fluid–structure interaction is not only highly computationally demanding but also requires …

Image-based immersed boundary model of the aortic root

A Hasan, EM Kolahdouz, A Enquobahrie… - Medical engineering & …, 2017 - Elsevier
Abstract Each year, approximately 300,000 heart valve repair or replacement procedures
are performed worldwide, including approximately 70,000 aortic valve replacement …

A data‐driven optimal control method for endoplasmic reticulum membrane compartmentalization in budding yeast cells

A Laadhari, Y Barral, G Székely - Mathematical Methods in the …, 2023 - Wiley Online Library
In this paper, we propose a variational data assimilation approach for including data
measurements in the simulation of the mobility of fluorescently labeled molecules in the …

[HTML][HTML] Eulerian finite element method for the numerical modeling of fluid dynamics of natural and pathological aortic valves

A Laadhari, G Székely - Journal of Computational and Applied Mathematics, 2017 - Elsevier
We present a finite element methodology tailored for the simulation of pulsatile flow in the
full aorta and sinus of Valsalva interacting with highly deformable thin leaflets. We describe …

A consistent and versatile computational approach for general fluid‐structure‐contact interaction problems

C Ager, A Seitz, WA Wall - International Journal for Numerical …, 2021 - Wiley Online Library
We present a consistent approach that allows to solve challenging general nonlinear fluid‐
structure‐contact interaction (FSCI) problems. The underlying formulation includes both “no …

A multiscale computational modeling for cerebral blood flow with aneurysms and/or stenoses

H Yu, GP Huang, Z Yang… - International Journal for …, 2018 - Wiley Online Library
Abstract A 1‐dimensional (1D)‐3‐dimensional (3D) multiscale model for the human vascular
network was proposed by combining a low‐fidelity 1D modeling of blood circulation to …