Extracellular matrix remodeling in vascular disease: defining its regulators and pathological influence

PK Lin, GE Davis - Arteriosclerosis, Thrombosis, and Vascular …, 2023 - Am Heart Assoc
Because of structural and cellular differences (ie, degrees of matrix abundance and cross-
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …

Diabetic microvascular disease in non-classical beds: the hidden impact beyond the retina, the kidney, and the peripheral nerves

D Mauricio, M Gratacòs, J Franch-Nadal - Cardiovascular Diabetology, 2023 - Springer
Diabetes microangiopathy, a hallmark complication of diabetes, is characterised by
structural and functional abnormalities within the intricate network of microvessels beyond …

Arterial dissections: Common features and new perspectives

M Bax, V Romanov, K Junday… - Frontiers in …, 2022 - frontiersin.org
Arterial dissections, which involve an abrupt tear in the wall of a major artery resulting in the
intramural accumulation of blood, are a family of catastrophic disorders causing major …

The adventitia in arterial development, remodeling, and hypertension

MW Majesky, MCM Weiser-Evans - Biochemical pharmacology, 2022 - Elsevier
The adventitia receives input signals from the vessel wall, the immune system, perivascular
nerves and from surrounding tissues to generate effector responses that regulate structural …

[HTML][HTML] Immune and non-immune mechanisms that determine vasculitis and coronary artery aneurysm topography in Kawasaki disease and MIS-C

S Giryes, D McGonagle - Autoimmunity Reviews, 2023 - Elsevier
The overlap between multisystem inflammatory syndrome in children (MIS-C) and Kawasaki
disease (KD) including coronary artery aneurysms (CAA) and broadly shared …

Single cell transcriptomics of fibrotic lungs unveils aging-associated alterations in endothelial and epithelial cell regeneration

AA Raslan, TX Pham, J Lee, J Hong, J Schmottlach… - bioRxiv, 2023 - biorxiv.org
Lung regeneration deteriorates with aging leading to increased susceptibility to pathologic
conditions, including fibrosis. Here, we investigated bleomycin-induced lung injury …

Advances in the physiology of transvascular exchange and a new look at rational fluid prescription

ME Alamilla-Sanchez, MA Alcala-Salgado… - … Journal of General …, 2023 - Taylor & Francis
The Starling principle is a model that explains the transvascular distribution of fluids
essentially governed by hydrostatic and oncotic forces, which dynamically allow vascular …

Multiscale Structure and Function of the Aortic Valve Apparatus

H El-Nashar, M Sabry, YT Tseng… - Physiological …, 2023 - journals.physiology.org
While studying the aortic valve in isolation has facilitated the development of life-saving
procedures and technologies, the dynamic interplay of the aortic valve and its surrounding …

Overcoming big bottlenecks in vascular regeneration

DA Fantini, G Yang, A Khanna, D Subramanian… - Communications …, 2024 - nature.com
Bioengineering and regenerative medicine strategies are promising for the treatment of
vascular diseases. However, current limitations inhibit the ability of these approaches to be …

Artificial Vasa‐Vasorum Serves as an On‐Site Regenerative Promoter of Cell‐Free Vascular Grafting

H Ha, S Baek, K Lee, S Cho, MJ Cho… - Advanced Functional …, 2024 - Wiley Online Library
The control paradigm of small vessel pathophysiology has changed to focus on the vascular
out‐wall rather than the lumen‐intimal factors. As an emerging controller of the external wall …