Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by
antinuclear antibodies (ANAs) that form immune complexes that mediate pathogenesis by …

Historically, rheumatic diseases have not received much attention in Africa, particularly in
sub-Saharan Africa, possibly owing to a focus on the overwhelming incidence of infectious …

The European League against Rheumatism/American College of Rheumatology
(EULAR/ACR) classification criteria for systemic lupus erythematosus (SLE) 1, 2 were …

ABSTRACT Introduction The European League Against Rheumatism/American College of
Rheumatology (EULAR/ACR) classification criteria for systemic lupus erythematosus (SLE) …

Objectives Antiphosphatidylserine/prothrombin complex antibodies (aPS/PT) are risk factors
for thrombosis, yet further validation of their clinical relevance in different ethnic groups is …

Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory
disease with manifestations ranging from mild to life-threatening organ dysfunction. There is …

The new classification criteria have been investigated in an impressive number of cohorts
worldwide, adding to the data from the EULAR/ACR criteria project cohort. It is critical to …

Objectives Emerging evidence demonstrates that aPS-PT associate with thrombotic events.
Genetic predisposition, including HLA-DRB1 alleles, is known to contribute to the …

Abstract Objectives In SLE, anti-dsDNA can co-occur with autoantibodies against other
chromatin components, like histones and nucleosomes. These antibodies induce type-1 …

In rheumatic diseases, damage is a major concern and reflects irreversible organ scarring or
tissue degradation. Quantifying damage or measuring its severity is an indispensable …