Adenovirus vector-based vaccine for infectious diseases

F Sakurai, M Tachibana, H Mizuguchi - Drug Metabolism and …, 2022 - Elsevier
Replication-incompetent adenovirus (Ad) vectors have been widely used as gene delivery
vehicles in both gene therapy studies and basic studies for gene function analysis due to …

[HTML][HTML] Monkeypox virus: An emerging epidemic

AAA Aljabali, MA Obeid, MB Nusair, A Hmedat… - Microbial …, 2022 - Elsevier
Introduction A monkeypox outbreak is spreading in territories where the virus is not
generally prevalent. The rapid and sudden emergence of monkeypox in numerous nations …

Knowledge and attitude regarding monkeypox virus among physicians in Saudi Arabia: a cross-sectional study

NZ Alshahrani, MR Algethami, AM Alarifi, F Alzahrani… - Vaccines, 2022 - mdpi.com
The growing incidence of human monkeypox cases emphasizes the significance of
prevention, early detection, and prompt responses for healthcare providers. The aim of this …

[HTML][HTML] Respiratory syncytial virus: from pathogenesis to potential therapeutic strategies

Z Shang, S Tan, D Ma - International Journal of Biological Sciences, 2021 - ncbi.nlm.nih.gov
Respiratory syncytial virus (RSV) is one of the most important viral pathogens causing
respiratory tract infection in infants, the elderly and people with poor immune function, which …

[HTML][HTML] Vaccine development throughout history

A Saleh, S Qamar, A Tekin, R Singh, R Kashyap - Cureus, 2021 - ncbi.nlm.nih.gov
The emergence of the coronavirus disease 2019 (COVID-19) pandemic has made us
appreciate how important it is to quickly develop treatments and save lives. The race to …

Human monkeypox (hMPXV) re‐emergence: host immunity status and current vaccines landscape

M Shafaati, M Zandi - Journal of medical virology, 2023 - Wiley Online Library
Monkeypox virus is a member of the Orthopoxvirus genus and the Poxviridae family.
Orthopoxviruses are among the most intricate animal viruses. The pathogenicity of human …

Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection

JD Albarnaz, J Kite, M Oliveira, H Li, Y Di… - Nature …, 2023 - nature.com
Modified vaccinia Ankara (MVA) virus does not replicate in human cells and is the vaccine
deployed to curb the current outbreak of mpox. Here, we conduct a multiplexed proteomic …

Monkeypox virus: past and present

YM Dou, H Yuan, HW Tian - World Journal of Pediatrics, 2023 - Springer
Background The objective of this paper is to analyze the current status of monkeypox
worldwide. In the face of this public health threat, our purpose is to elucidate the clinical …

Reduced respiratory syncytial virus load, symptoms, and infections: a human challenge trial of MVA-BN-RSV vaccine

E Jordan, G Kabir, S Schultz… - The Journal of …, 2023 - academic.oup.com
Background Respiratory syncytial virus (RSV) causes significant disease burden in older
adults. MVA-BN-RSV is a novel poxvirus-vectored vaccine encoding internal and external …

Travel vaccines throughout history

A Pavli, HC Maltezou - Travel medicine and infectious disease, 2022 - Elsevier
Vaccinations are an important component of travel medicine. Beyond protection of travelers,
vaccines are administered to prevent the importation of vaccine-preventable diseases at …