A feasible protocol that uses atomic groups (KSCN, KSeCN, and NH2CN), o-bromobenzoyl
hydrazides, and formyls as reaction factors to synthesize N-fused 1, 2, 4-triazole with …

Abstract Bis (3-indolyl) methanes (BIM) are important and present in the structure of many
alkaloid and bioactive compounds (anti-inflammatory, anticancer, antiobesity, antimicrobial …

A series of novel nitrogen mustard-evodiamine hybrids were synthesized and evaluated for
their antitproliferative properties. The antiproliferative activities of 10a–d, 11a–d, and 12a–d …

β-Carboline and γ-lactone moieties have been selected by nature as privileged scaffolds
and display a wide range of pharmacological properties. Following nature, we envisaged …

A green and efficient synthesis of benzo [d][1, 3] thiazines through a base-promoted
cyclization reaction of o-isothiocyanato arylacetylenes with aroylacetonitriles has been …

Evodiamine (EVO) is a natural quinolone alkaloid firstly isolated from the fruit of Evodia
rutaecarpa, which is one of the most frequently used traditional Chinese herb for treating a …

A new route for the synthesis of 2-aminopyridines has been developed that merges C–H
functionalization with amide alcoholysis. The key component of this method is the ability of a …

The bismuth-catalyzed oxidative condensation of aldehydes with 2-aminobenzamide under
aerobic conditions is reported using ethanol as the solvent. Good to excellent isolated yields …

We live in a world with complex diseases such as cancer which cannot be cured with one-
compound one-target based therapeutic paradigm. This could be due to the involvement of …

The organocatalytic asymmetric Mannich reaction has always been an area of active interest
in the community of chemistry. The Mannich products, optically active β‐amino− carbonyl …