In (OTf) 3 catalysed an expeditious synthesis of β-carboline–imidazo [1, 2-a] pyridine and imidazo [1, 2-a] pyrazine conjugates
β-Carboline containing alkaloids are ubiquitously present in Nature, while imidazo [1, 2-a]
pyridine nucleus is incorporated in various synthetic commercial drugs and biologically …
pyridine nucleus is incorporated in various synthetic commercial drugs and biologically …
Iodine Catalysed Synthesis of Luminescent β‐Carboline Tethered Thiazolo[4,5‐c]carbazole and Naphtho[2,1‐d]thiazole Derivatives and Estimation of their Light …
A Simple, convenient and highly efficient I2‐catalysed approach has been unfolded towards
the synthesis of highly fluorescent β‐carboline C‐1 (3)‐tethered thiazolo [4, 5‐c] carbazoles …
the synthesis of highly fluorescent β‐carboline C‐1 (3)‐tethered thiazolo [4, 5‐c] carbazoles …
Phosphoric acid catalyzed asymmetric [2+ 2] cyclization/penicillin–penillonic acid rearrangement
M Zhang, C Yu, J Xie, X Xun, W Sun… - Angewandte …, 2018 - Wiley Online Library
Enantioselective synthesis of imidazolidin‐5‐ones through a phosphoric acid catalyzed
reaction between azlactones and N‐substituted β‐carbolines is reported. The reaction takes …
reaction between azlactones and N‐substituted β‐carbolines is reported. The reaction takes …
Exploration of Benzo [b] carbazole-6, 11-diones as anticancer agents: Synthesis and studies of hTopoIIα inhibition and apoptotic effects
S Sisodiya, S Paul, H Chaudhary, P Grewal… - Bioorganic & Medicinal …, 2021 - Elsevier
Two series of (hetero) arylamino-naphthoquinones and benzo-fused carbazolequinones
were considered for study with the rationale that related structural motifs are present in …
were considered for study with the rationale that related structural motifs are present in …
Fused Imidazo [2, 1‐b][1, 2, 3] triazolo [4, 5‐d][1, 3] thiazines: One‐Pot Synthesis, Antibiofilim, Bactericidal Effects, and in silico Studies
N Ramu, TM Krishna, V Nasipireddy… - …, 2023 - Wiley Online Library
It has been reported that biologically active organic probe underwent a highly adaptive,
efficient and selective “Click followed by C− N bond coupling” by the use of PEG‐400 in …
efficient and selective “Click followed by C− N bond coupling” by the use of PEG‐400 in …
Discovery of fluorinated 2‑Styryl 4 (3H)-quinazolinone as potential therapeutic hit for oral cancer
DP Satpute, U Shirwadkar, AK Tharalla… - Bioorganic & Medicinal …, 2023 - Elsevier
Oral squamous cell carcinoma (OSCC) is the most common malignant epithelial neoplasm,
affects the mouth and throat, and accounts for 90% of oral cancers. Considering the …
affects the mouth and throat, and accounts for 90% of oral cancers. Considering the …
Discovery of novel bis-evodiamine derivatives with potent antitumor activity
H Liang, W Wang, F Zhu, S Chen, D Liu… - Bioorganic & Medicinal …, 2022 - Elsevier
Inspired by antitumor natural product evodiamine, a series of novel bis-evodiamine
derivatives were designed and synthesized, which showed potent antitumor activity. In …
derivatives were designed and synthesized, which showed potent antitumor activity. In …
Copper-catalyzed oxidative cleavage of Passerini and Ugi adducts in basic medium yielding α-ketoamides
The aerobic oxidative cleavage of Passerini and Ugi adducts in the presence of base and
copper (I) iodide is studied in detail. The oxidative cleavage yields α-ketoamides along with …
copper (I) iodide is studied in detail. The oxidative cleavage yields α-ketoamides along with …
Inspired by bis-β-carboline alkaloids: Construction and antitumor evaluation of a novel bis-β-carboline scaffold as potent antitumor agents
W Liu, M Wang, Z Guo, Y He, H Jia, J He, S Miao… - Bioorganic …, 2023 - Elsevier
Bis-β-carboline alkaloids are widely distributed in natural products and represent a
promising drug-like scaffold for discovering drugs and bioactive molecules. In this study, we …
promising drug-like scaffold for discovering drugs and bioactive molecules. In this study, we …
Design, synthesis and biological evaluation of 3-arylisoquinoline derivatives as topoisomerase I and II dual inhibitors for the therapy of liver cancer
X Deng, T Luo, X Zhang, Y Li, L Xie, W Jiang… - European Journal of …, 2022 - Elsevier
To explore novel topoisomerase inhibitors with high activity and druggability, 3-aryl
isoquinoline alkaloids based on the corydamine modification and preliminary SARs of …
isoquinoline alkaloids based on the corydamine modification and preliminary SARs of …