A potential DIPEA‐assisted approach has been unfolded for the synthesis of novel β‐
carboline tethered‐4H‐pyran derivatives via one‐pot condensation of 1‐formyl‐9H‐β …

The heat shock protein (HSP) system is essential for the conformational stability and function
of several proteins. Therefore, the development of efficacious HSP-targeting anticancer …

Abstract A series of 1, 3-benzothiazinone derivatives were designed and synthesized for
pharmacological assessments. Among the synthesized 19 compounds, some compounds …

A simple and highly efficient one‐pot, metal‐free approach has been developed for the
synthesis of β‐carboline− pyrazole/− pyrazoline‐based molecular hybrids. The synthesis of …

In recent years, benzimidates and benzamidines have received tremendous importance as
starting materials owing to their electronic properties and high reactivity. Their application as …

Die Gerüstdiversität ist ein entscheidendes Merkmal von Verbindungskollektionen, das
einen großen Einfluss auf deren Erfolg beim biologischen Screening hat. Die Synthese …

Combretastatin A-4 (CA-4) is a potent inhibitor of tubulin polymerization and a colchicine
binding site inhibitor (CBSI). The structure-activity relationship study of CA-4 showed that the …

Bisindolylmethanes (3, 3'-BIMs) compounds are important indole alkyloads and their units
are widely found in various natural products, functional materials and synthetic …

Natural products as starting templates have shown historically major contribution to
development of drugs. Inspired by the structure–function of an anticancer natural alkaloid …

The increase in the application of herbal medicines and dietary products over the last
decades has been accompanied with a substantial increase in case reports of herb-induced …