In Vivo Metabolic Imaging of [1‐13C]Pyruvate‐d3 Hyperpolarized By Reversible Exchange With Parahydrogen**
H de Maissin, PR Groß, O Mohiuddin… - Angewandte Chemie …, 2023 - Wiley Online Library
Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …
Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): Recent advances and applications
OG Salnikov, DB Burueva, IV Skovpin… - Mendeleev …, 2023 - Elsevier
Signal amplification by reversible exchange (SABRE) is a rapidly developing nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
MATRESHCA: Microtesla Apparatus for Transfer of Resonance Enhancement of Spin Hyperpolarization via Chemical Exchange and Addition
We present an integrated, open-source device for parahydrogen-based hyperpolarization
processes in the microtesla field regime with a cost of components of less than $7000. The …
processes in the microtesla field regime with a cost of components of less than $7000. The …
[HTML][HTML] Quo Vadis Hyperpolarized 13C MRI?
Over the last two decades, hyperpolarized 13 C MRI has gained significance in both
preclinical and clinical studies, hereby relying on technologies like PHIP-SAH …
preclinical and clinical studies, hereby relying on technologies like PHIP-SAH …
Delivering Robust Proton-Only Sensing of Hyperpolarized [1,2-13C2]-Pyruvate Using Broad-Spectral-Range Nuclear Magnetic Resonance Pulse Sequences
I Mandzhieva, I Adelabu, S Nantogma… - ACS …, 2023 - ACS Publications
Hyperpolarized [1-13C] pyruvate is the leading hyperpolarized injectable contrast agent and
is currently under evaluation in clinical trials for molecular imaging of metabolic diseases …
is currently under evaluation in clinical trials for molecular imaging of metabolic diseases …
Spying on parahydrogen-induced polarization transfer using a half-tesla benchtop MRI and hyperpolarized imaging enabled by automation
Nuclear spin hyperpolarization is a quantum effect that enhances the nuclear magnetic
resonance signal by several orders of magnitude and has enabled real-time metabolic …
resonance signal by several orders of magnitude and has enabled real-time metabolic …
15N Hyperpolarization of Metronidazole Antibiotic in Aqueous Media Using Phase-Separated Signal Amplification by Reversible Exchange with Parahydrogen
SV Sviyazov, DB Burueva, NV Chukanov… - The Journal of …, 2024 - ACS Publications
Metronidazole is a prospective hyperpolarized MRI contrast agent with potential hypoxia
sensing utility for applications in cancer, stroke, neurodegenerative diseases, etc. We …
sensing utility for applications in cancer, stroke, neurodegenerative diseases, etc. We …
Water-Compatible and Recyclable Heterogeneous SABRE Catalyst for NMR Signal Amplification
A water-compatible and recyclable catalyst for nuclear magnetic resonance (NMR)
hyperpolarization via signal amplification by reversible exchange (SABRE) was developed …
hyperpolarization via signal amplification by reversible exchange (SABRE) was developed …
Parahydrogen in Reversible Exchange Induces Long-Lived 15N Hyperpolarization of Anticancer Drugs Anastrozole and Letrozole
K MacCulloch, A Browning, P TomHon… - Analytical …, 2023 - ACS Publications
Hyperpolarization modalities overcome the sensitivity limitations of NMR and unlock new
applications. Signal amplification by reversible exchange (SABRE) is a particularly cheap …
applications. Signal amplification by reversible exchange (SABRE) is a particularly cheap …
J Coupling Constants of <1 Hz Enable 13C Hyperpolarization of Pyruvate via Reversible Exchange of Parahydrogen
CD Assaf, X Gui, AA Auer, SB Duckett… - The Journal of …, 2024 - ACS Publications
Observing pyruvate metabolism in vivo has become a focal point of molecular magnetic
resonance imaging. Signal amplification by reversible exchange (SABRE) has recently …
resonance imaging. Signal amplification by reversible exchange (SABRE) has recently …