Biofilms in diabetic foot ulcers: significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

Topical antimicrobial agents for treating foot ulcers in people with diabetes

JC Dumville, BA Lipsky, C Hoey… - Cochrane Database …, 2017 - cochranelibrary.com
Background People with diabetes are at high risk for developing foot ulcers, which often
become infected. These wounds, especially when infected, cause substantial morbidity …

[PDF][PDF] IWGDF guidance on the diagnosis and management of foot infections in persons with diabetes

BA Lipsky, J Aragón-Sánchez, M Diggle… - Diabetes Metab Res …, 2016 - aogp.com.au
23. Do not select a specific type of dressing for a diabetic foot infection with the aim of
preventing an infection or improving its outcome (strong; high). 24. For diabetic foot …

Antimicrobial stewardship in wound care: a position paper from the British Society for Antimicrobial Chemotherapy and European Wound Management Association

BA Lipsky, M Dryden, F Gottrup… - Journal of …, 2016 - academic.oup.com
Background With the growing global problem of antibiotic resistance it is crucial that
clinicians use antibiotics wisely, which largely means following the principles of …

Microbiology of diabetic foot infections: from Louis Pasteur to 'crime scene investigation'

A Spichler, BL Hurwitz, DG Armstrong, BA Lipsky - BMC medicine, 2015 - Springer
Were he alive today, would Louis Pasteur still champion culture methods he pioneered over
150 years ago for identifying bacterial pathogens? Or, might he suggest that new molecular …

[HTML][HTML] The diabetic foot microbiota: A review

J Jneid, JP Lavigne, B La Scola, N Cassir - Human Microbiome Journal, 2017 - Elsevier
Diabetes mellitus represents a major public health threat worldwide. A serious complication
of diabetes is the development of foot ulcers which, when they become infected, are the …

Susceptibility patterns of Staphylococcus aureus biofilms in diabetic foot infections

C Mottola, CS Matias, JJ Mendes, J Melo-Cristino… - BMC microbiology, 2016 - Springer
Background Foot infections are a major cause of morbidity in people with diabetes and the
most common cause of diabetes-related hospitalization and lower extremity amputation …

The role of anaerobes in diabetic foot infections

PGP Charles, I Uçkay, B Kressmann, S Emonet… - Anaerobe, 2015 - Elsevier
Diabetic foot infections (DFI) are a common cause of morbidity and, on occasion, even
mortality. Infection can be either mono-or polymicrobial, with a wide variety of potential …

Neutralizing Staphylococcus aureus virulence with AZD6389, a three mAb combination, accelerates closure of a diabetic polymicrobial wound

C Tkaczyk, O Jones-Nelson, YY Shi, DE Tabor… - Msphere, 2022 - Am Soc Microbiol
Nonhealing diabetic foot ulcers (DFU), a major complication of diabetes, are associated with
high morbidity and mortality despite current standard of care. Since Staphylococcus aureus …

Mini review therapeutic strategies targeting for biofilm and bone infections

S Wu, B Wu, Y Liu, S Deng, L Lei, H Zhang - Frontiers in Microbiology, 2022 - frontiersin.org
Bone infection results in a complex inflammatory response and bone destruction. A broad
spectrum of bacterial species has been involved for jaw osteomyelitis, hematogenous …