Precise and controlled drug delivery to treat periodontitis in patients with diabetes remains a
significant clinical challenge. Nanoparticle-based drug delivery systems offer a potential …

Respiratory diseases, including lung cancer, pulmonary fibrosis, asthma, and the recently
emerging fatal coronavirus disease-19 (COVID-19), are the leading causes of illness and …

Apical periodontitis is an inflammatory response caused by pulp infection. It induces bone
resorption in the apical and periapical regions of the tooth. The most conservative approach …

Objectives Oestrogen deficiency is an aetiological factor of postmenopausal osteoporosis
(PMO), which not only decreases bone density in vertebrae and long bone but also …

Purpose To evaluate the kinetics of apical periodontitis development in vivo, induced either
by contamination of the root canals by microorganisms from the oral cavity or by inoculation …

Background The aim of this double‐blind randomized placebo‐controlled clinical trial was to
evaluate the efficacy of a multinutrient supplement as an add‐on therapy to scaling and root …

Alpha-lipoic acid (ALA) is extensively utilized in multivitamin formulas and anti-aging
products. The purpose of this study was to investigate the potential protective benefits of ALA …

This study aimed to investigate if apical periodontitis in different periods changes systemic
levels of the antioxidant and pro-oxidant parameters in Wistar rats. Twenty-four rats were …

Irinotecan (CPT-11) is a chemotherapeutic agent involved in the treatment regimens for
several malignancies such as colorectal cancer. N-acetylcysteine (NAC) is a strong …

Aim This study aimed to investigate the potential protective effects of N‐acetyl‐L‐cysteine
(NAC) against apical periodontitis (AP) in rats with adriamycin (ADR)‐induced kidney and …