Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies

FM Kashkooli, M Soltani, M Souri - Journal of controlled release, 2020 - Elsevier
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

[HTML][HTML] Adapting liposomes for oral drug delivery

H He, Y Lu, J Qi, Q Zhu, Z Chen, W Wu - Acta pharmaceutica sinica B, 2019 - Elsevier
Liposomes mimic natural cell membranes and have long been investigated as drug carriers
due to excellent entrapment capacity, biocompatibility and safety. Despite the success of …

Role of nanoparticle size, shape and surface chemistry in oral drug delivery

A Banerjee, J Qi, R Gogoi, J Wong… - Journal of Controlled …, 2016 - Elsevier
Nanoparticles find intriguing applications in oral drug delivery since they present a large
surface area for interactions with the gastrointestinal tract and can be modified in various …

Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology

N Bertrand, J Wu, X Xu, N Kamaly… - Advanced drug delivery …, 2014 - Elsevier
Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …

[HTML][HTML] Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

P Lundquist, P Artursson - Advanced drug delivery reviews, 2016 - Elsevier
In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

Functionalizing PLGA and PLGA derivatives for drug delivery and tissue regeneration applications

C Martins, F Sousa, F Araujo… - Advanced healthcare …, 2018 - Wiley Online Library
Abstract Poly (lactic‐co‐glycolic) acid (PLGA) is one of the most versatile biomedical
polymers, already approved by regulatory authorities to be used in human research and …

[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport

Z Zhang, Y Lu, J Qi, W Wu - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …

A holistic approach to targeting disease with polymeric nanoparticles

CJ Cheng, GT Tietjen, JK Saucier-Sawyer… - Nature reviews Drug …, 2015 - nature.com
The primary goal of nanomedicine is to improve clinical outcomes. To this end, targeted
nanoparticles are engineered to reduce non-productive distribution while improving …

Transporter-guided delivery of nanoparticles to improve drug permeation across cellular barriers and drug exposure to selective cell types

L Kou, YD Bhutia, Q Yao, Z He, J Sun… - Frontiers in …, 2018 - frontiersin.org
Targeted nano-drug delivery systems conjugated with specific ligands to target selective cell-
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …

Oral delivery of biologics for precision medicine

M Durán‐Lobato, Z Niu, MJ Alonso - Advanced Materials, 2020 - Wiley Online Library
The emerging field of precision medicine is rapidly growing, fostered by the advances in
genome mapping and molecular diagnosis. In general, the translation of these advances …