A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation
The specialized microfold cells (M cells) in the follicle-associated epithelium (FAE) of
intestinal Peyer's patches serve as antigen-sampling cells of the intestinal innate immune …
intestinal Peyer's patches serve as antigen-sampling cells of the intestinal innate immune …
Recent advances in gold and silver nanoparticle based therapies for lung and breast cancers
P Malik, TK Mukherjee - International Journal of Pharmaceutics, 2018 - Elsevier
In recent years, gold (Au) and silver (Ag) nanoparticles (NPs) have been the centerstage of
improving cancer treatments and therapies, substantially attributed to their size and shape …
improving cancer treatments and therapies, substantially attributed to their size and shape …
Targeting tumor highly-expressed LAT1 transporter with amino acid-modified nanoparticles: toward a novel active targeting strategy in breast cancer therapy
L Li, X Di, M Wu, Z Sun, L Zhong, Y Wang, Q Fu… - … , Biology and Medicine, 2017 - Elsevier
Designing active targeting nanocarriers with increased cellular accumulation of
chemotherapeutic agents is a promising strategy in cancer therapy. Herein, we report a …
chemotherapeutic agents is a promising strategy in cancer therapy. Herein, we report a …
Microfluidic manipulation of core/shell nanoparticles for oral delivery of chemotherapeutics: a new treatment approach for colorectal cancer
MM Hasani-Sadrabadi, S Taranejoo… - Advanced …, 2016 - epublications.marquette.edu
A microfluidics approach to synthesize core–shell nanocarriers with high pH tunability is
described. The sacrificial shell protects the core layer with the drugs and prevents their …
described. The sacrificial shell protects the core layer with the drugs and prevents their …
The optimized delivery of triterpenes by liposomal nanoformulations: Overcoming the challenges
A Milan, A Mioc, A Prodea, M Mioc, R Buzatu… - International journal of …, 2022 - mdpi.com
The last decade has witnessed a sustained increase in the research development of modern-
day chemo-therapeutics, especially for those used for high mortality rate pathologies …
day chemo-therapeutics, especially for those used for high mortality rate pathologies …
Dextran–protamine coated nanostructured lipid carriers as mucus-penetrating nanoparticles for lipophilic drugs
The main objectives of the present study were (i) to evaluate the effect of the mucus layer on
saquinavir-loaded nanostructured lipid carriers (SQV-NLCs) uptake and (ii) to evaluate the …
saquinavir-loaded nanostructured lipid carriers (SQV-NLCs) uptake and (ii) to evaluate the …
Functionalized materials for multistage platforms in the oral delivery of biopharmaceuticals
Recent developments in materials science and specific surface functionalization of materials
are providing new tools for the rational design of precisely engineered drug delivery …
are providing new tools for the rational design of precisely engineered drug delivery …
Bioinspired butyrate-functionalized nanovehicles for targeted oral delivery of biomacromolecular drugs
L Wu, M Liu, W Shan, X Zhu, L Li, Z Zhang… - Journal of Controlled …, 2017 - Elsevier
Ligand-functionalization can increase the affinity of nanoparticles (NPs) with targeted cells.
However, one major defect of ligands still exists in oral administration: limited receptor …
However, one major defect of ligands still exists in oral administration: limited receptor …
[HTML][HTML] Biomimetic thiamine-and niacin-decorated liposomes for enhanced oral delivery of insulin
Biomimetic nanocarriers are emerging as efficient vehicles to facilitate dietary absorption of
biomacromolecules. In this study, two vitamins, thiamine and niacin, are employed to …
biomacromolecules. In this study, two vitamins, thiamine and niacin, are employed to …
Airway epithelial-targeted nanoparticle reverses asthma in inhalation therapy
Y Yu, M Ni, Y Zheng, Y Huang - Journal of Controlled Release, 2024 - Elsevier
Despite extensive research on corticosteroids for treating asthma, their short residence time
in the lungs has limited their therapeutic effects in vivo. Nanoparticles have been widely …
in the lungs has limited their therapeutic effects in vivo. Nanoparticles have been widely …