HIV-1 drug resistance and resistance testing
DS Clutter, MR Jordan, S Bertagnolio… - Infection, Genetics and …, 2016 - Elsevier
The global scale-up of antiretroviral (ARV) therapy (ART) has led to dramatic reductions in
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …
[HTML][HTML] HIV and drug-resistant subtypes
BM Nastri, P Pagliano, C Zannella, V Folliero… - Microorganisms, 2023 - mdpi.com
Acquired Immunodeficiency Syndrome (AIDS) is a human viral infectious disease caused by
the positive-sense single-stranded (ss) RNA Human Immunodeficiency Virus …
the positive-sense single-stranded (ss) RNA Human Immunodeficiency Virus …
Virologic efficacy of tenofovir, lamivudine and dolutegravir as second-line antiretroviral therapy in adults failing a tenofovir-based first-line regimen
Objective: Recycling tenofovir and lamivudine/emtricitabine (XTC) with dolutegravir would
provide a more tolerable, affordable, and scalable second-line regimen than dolutegravir …
provide a more tolerable, affordable, and scalable second-line regimen than dolutegravir …
[HTML][HTML] HIV-1 drug resistance mutations: potential applications for point-of-care genotypic resistance testing
SY Rhee, MR Jordan, E Raizes, A Chua, N Parkin… - PloS one, 2015 - journals.plos.org
The increasing prevalence of acquired and transmitted HIV-1 drug resistance is an obstacle
to successful antiretroviral therapy (ART) in the low-and middle-income countries (LMICs) …
to successful antiretroviral therapy (ART) in the low-and middle-income countries (LMICs) …
Intensive adherence counselling for HIV‐infected individuals failing second‐line antiretroviral therapy in Johannesburg, South Africa
Objective In resource‐limited settings, where genotypic drug resistance testing is rarely
performed and poor adherence is the most common reason for treatment failure …
performed and poor adherence is the most common reason for treatment failure …
[HTML][HTML] Third-line antiretroviral therapy program in the South African public sector: cohort description and virological outcomes
M Moorhouse, G Maartens, WDF Venter… - JAIDS Journal of …, 2019 - journals.lww.com
Background: The World Health Organization recommends that antiretroviral therapy (ART)
programs in resource-limited settings develop third-line ART policies. South Africa …
programs in resource-limited settings develop third-line ART policies. South Africa …
HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa
K Steegen, M Bronze… - Journal of …, 2016 - academic.oup.com
Background Routine HIV-1 antiretroviral drug resistance testing for patients failing NNRTI-
based regimens is not recommended in resource-limited settings. Therefore, surveys are …
based regimens is not recommended in resource-limited settings. Therefore, surveys are …
Protease inhibitor resistance in the first 3 years of second-line antiretroviral therapy for HIV-1 in sub-Saharan Africa
TS Boender, RL Hamers, P Ondoa… - The Journal of …, 2016 - academic.oup.com
Background. As antiretroviral therapy (ART) programs in sub-Saharan Africa mature,
increasing numbers of persons with human immunodeficiency virus (HIV) infection will …
increasing numbers of persons with human immunodeficiency virus (HIV) infection will …
HIV-1 second-line failure and drug resistance at high-level and low-level viremia in Western Kenya
R Kantor, A DeLong, L Schreier, M Reitsma, E Kemboi… - Aids, 2018 - journals.lww.com
Objective: Characterize failure and resistance above and below guidelines-recommended
1000 copies/ml virologic threshold, upon second-line failure. Design: Cross-sectional study …
1000 copies/ml virologic threshold, upon second-line failure. Design: Cross-sectional study …
Rates of virological suppression and drug resistance in adult HIV-1-positive patients attending primary healthcare facilities in KwaZulu-Natal, South Africa
Abstract Background KwaZulu-Natal (KZN) Province in South Africa has the highest HIV
disease burden in the country, with an estimated population prevalence of 24.7%. A pilot …
disease burden in the country, with an estimated population prevalence of 24.7%. A pilot …