This User's Guide is intended to support the design, implementation, analysis, interpretation,
and quality evaluation of registries created to increase understanding of patient outcomes …

The ACC/AHA ST-Elevation and Non–ST-Elevation Myocardial Infarction (STEMI/NSTEMI)
Performance Measures Writing Committee (the writing committee) was charged with the …

Importance Acute myocardial infarction (AMI) complicated by cardiogenic shock is
associated with substantial morbidity and mortality. Although intravascular microaxial left …

Background—The HEART Pathway is a decision aid designed to identify emergency
department patients with acute chest pain for early discharge. No randomized trials have …

Context High platelet reactivity while receiving clopidogrel has been linked to cardiovascular
events after percutaneous coronary intervention (PCI), but a treatment strategy for this issue …

Background Admission rates among patients presenting to emergency departments with
possible acute coronary syndromes are high, although for most of these patients, the …

Background Lipid-lowering therapy with statins reduces the risk of cardiovascular events,
but the optimal level of low-density lipoprotein (LDL) cholesterol is unclear. Methods We …

Background Vitamin K antagonists reduce the risk of stroke in patients with atrial fibrillation
but are considered unsuitable in many patients, who usually receive aspirin instead. We …

Objectives: The purpose of this study was to determine whether a new accelerated
diagnostic protocol (ADP) for possible cardiac chest pain could identify low-risk patients …

Background The combined use of anticoagulants, antiplatelet agents, and invasive coronary
procedures reduces ischemic coronary events but also increases bleeding in patients with …